Successful Treatment of Multiple Small-Intestinal Perforations Caused by Epstein-Barr Virus-Positive Malignant Lymphoma in a Child

被引：0
作者：
Zhang, Xianwei [1 ]
Zhang, Wancun [1 ]
Wang, Huanmin [2 ,3 ]
Zhou, Qiang [4 ]
机构：
[1] Zhengzhou Univ, Dept Pediat Oncol Surg, Childrens Hosp, Zhengzhou 450018, Peoples R China
[2] Capital Med Univ, Dept Pediat Oncol Surg, Natl Ctr Childrens Hlth, Beijing 100045, Peoples R China
[3] Capital Med Univ, Beijing Childrens Hosp, Beijing 100045, Peoples R China
[4] Zhengzhou Univ, Dept Pathol, Childrens Hosp, Zhengzhou 450018, Peoples R China
来源：
INDIAN JOURNAL OF SURGERY | 2020年 / 82卷 / 04期
关键词：
Intestine; Perforation; Lymphoma; Children; Epstein-Barr virus;
D O I：
10.1007/s12262-020-02074-5
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
Multiple small-intestinal perforations caused by Epstein-Barr virus-positive malignant lymphoma in children are rare in clinical practice. This article reports the case of a 17-month-old girl with multiple small-intestinal perforations caused by Epstein-Barr virus-positive malignant lymphoma. Closure of perforations was done, and severely involved intestine was resected. Pathological examination of the lesions showed Epstein-Barr virus-positive diffuse large B cell lymphoma (DLBCL). This patient recovered from the operation uneventfully and received a six-cycle regimen of rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone combination chemotherapy. For multiple perforation of the digestive tract, it is necessary to carefully explore and suture during the operation. In addition, pediatric DLBCL required timely chemotherapy after surgery.
引用
收藏
页码：744 / 746
页数：3
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