Autoimmune hepatitis/primary sclerosing cholangitis overlap syndrome in adults: report of three cases

被引：2

作者：

Mauricio Santos, Oscar ^{[1
]}

Munoz Ortiz, Edison ^{[1
]}

Perez, Camilo ^{[1
]}

Carlos Restrepo, Juan ^{[1
]}

机构：

[1] Univ Antioquia, HPTU, Grp Gastrohepatol & Trasplante Hepat, Medellin, Colombia

来源：

GASTROENTEROLOGIA Y HEPATOLOGIA | 2012年 / 35卷 / 04期

关键词：

Overlap syndrome; Autoimmune hepatitis; Primary sclerosing cholangitis; PREVALENCE; FREQUENCY; DIAGNOSIS;

D O I：

10.1016/j.gastrohep.2011.12.003

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Overlap syndromes are cases of liver diseases that share clinical, serological, histological and radiological criteria of autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC) or primary sclerosing cholangitis (PSC). No definitions have been fully established and therefore there is no solid evidence on the diagnosis and treatment. This article presents the cases of three adult patients with overlapping features of AIH and PSC. Orthotopic liver transplantation was considered the best therapeutic alternative due to advanced disease progression in one patient, while medical treatment was provided in the remaining two patients. (C) 2011 Elsevier Espana, S.L. and AEEH y AEG. All rights reserved.

引用

页码：254 / 258

页数：5

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