One-Pot Synthesis of 2-Amino-4-phenyl-6-(phenylsulfanyl)-3,5-dicyanopyridines in Ionic Liquids

被引：7
|
作者：
Tian, Jinjin [1 ]
Guo, Hongyun [1 ]
机构：
[1] Zhejiang Univ Technol, Coll Chem Engn & Mat Sci, Hangzhou 310014, Zhejiang, Peoples R China
来源：
CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2012年 / 32卷 / 01期
关键词：
aldehyde; malononitrile; thiol; ionic liquid; 2-amino-4-phenyl-6-(phenylsulfanyl)-3,5-dicyanopyridine; 3-COMPONENT SYNTHESIS;
D O I：
10.6023/cjoc1105133
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The one-pot reaction of aldehydes, malononitrile and thiols was investigated in different medium. It was found that in ionic liquid [bmim]BF4 this reaction could be finished in short time and gave the product 2-amino-4-phenyl-6- (phenylsullanyl)-3,5-dicyanopyridines in high yields without byproduct. This method has some distinct advantages such as mild reaction conditions, high yields and selectivity, environmental friendliness. Moreover, the ionic liquid could be recovered conveniently and reused.
引用
收藏
页码：193 / 196
页数：4
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