Usefulness of light Microscopy in lymph node fine needle aspiration biopsy

被引:6
作者
Egea, AS [1 ]
González, MAM [1 ]
Barrios, AP [1 ]
Masgrau, NA [1 ]
de Agustín, PD [1 ]
机构
[1] Hosp 12 Octubre, Dept Anat Patol, E-28041 Madrid, Spain
关键词
aspiration biopsy; lymphadenopathy; microscopy;
D O I
10.1159/000326735
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
OBJECTIVE: To evaluate light microscopic examination of lymph node fine needle aspiration biopsy (FNAB) in order to determine the indications for ancillary procedures and biopsy. STUDY DESIGN: Reports and smears from 693 consecutive lymph node FNABs were reviewed. Fifty-five cases were excluded because of inadequacy of the material, and another 26 were excluded because follow-up information was not available. RESULTS: Cytologically, 220 cases were diagnosed as positive for malignancy and 392 as negative. Global sensitivity was 94.1% and specificity 96.9%. Sensitivity was higher for nonlymphoid neoplasms (98.2%) than for lymphoproliferative disorders (82.8%). CONCLUSION: Lymph node FNAB is a cost-effective procedure, and with adequate cytologic examination and follow-up, a large number of biopsies and time-consuming ancillary techniques can be avoided.
引用
收藏
页码:364 / 368
页数:5
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