Cross-Species Induction and Enhancement of Antimicrobial Properties in Response to Gamma Irradiation in Exiguobacterium sp HKG 126

被引：18

作者：

Pathak, Rajiv ^{[1
]}

Kumar, Raj ^{[2
]}

Gautam, Hemant K. ^{[1
]}

机构：

[1] CSIR Inst Genom & Integrat Biol, Comparat Genom Unit, Delhi 110007, India

[2] DRDO, INMAS, Div Radiat Biotechnol, Delhi 110007, India

来源：

INDIAN JOURNAL OF MICROBIOLOGY | 2013年 / 53卷 / 02期

关键词：

Exiguobacterium sp; Gamma irradiation; Cross-species induction; Extraction of secondary metabolites; Antimicrobial activity;

D O I：

10.1007/s12088-013-0369-0

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A gram positive, extreme haloalkaliphilic, radioresistant bacterium was isolated from mangrove region of Kerala (India) which was characterized as Exiguobacterium sp. HKG-126 using morphological, physiological, biochemical and molecular characterization. Present investigation was undertaken to examine Exiguobacterium sp. as a potential source of broad-spectrum antimicrobial activity and enhancement in this activity was observed due to cross-species/cross-genera induction and also in response to high dose of gamma (gamma) irradiation. Individual studies on the antimicrobial activity of all the co-cultivated bacterial strains before and after mixed culture fermentation, showed excellent enhancement in antimicrobial activity of Exiguobacterium sp. against a variety of clinical pathogens. To the best of our knowledge, this is the first report showing existence of an extremely high radioresistant strain of (up to 15 kGy) Exiguobacterium sp.

引用

页码：130 / 136

页数：7

共 24 条

[1] Genome-wide study predicts promoter-G4 DNA motifs regulate selective functions in bacteria: radioresistance of D-radiodurans involves G4 DNA-mediated regulation [J].

Beaume, Nicolas ;

Pathak, Rajiv ;

Yadav, Vinod Kumar ;

Kota, Swathi ;

Misra, Hari S. ;

Gautam, Hemant K. ;

Chowdhury, Shantanu .

NUCLEIC ACIDS RESEARCH, 2013, 41 (01) :76-89

[2]

Bergey D. H., 1994, Bergey's manual of determinative bacteriology, V2

[3]

Demain A L, 1998, Int Microbiol, V1, P259

[4] Microbial technologies for the discovery of novel bioactive metabolites [J].

Donadio, S ;

Monciardini, P ;

Alduina, R ;

Mazza, P ;

Chiocchini, C ;

Cavaletti, L ;

Sosio, M ;

Puglia, AM .

JOURNAL OF BIOTECHNOLOGY, 2002, 99 (03) :187-198

[5] Cross-Species Induction of Antimicrobial Compounds, Biosurfactants and Quorum-Sensing Inhibitors in Tropical Marine Epibiotic Bacteria by Pathogens and Biofouling Microorganisms [J].

Dusane, Devendra H. ;

Matkar, Pratiek ;

Venugopalan, Valayam P. ;

Kumar, Ameeta Ravi ;

Zinjarde, Smita S. .

CURRENT MICROBIOLOGY, 2011, 62 (03) :974-980

[6] Current approaches to exploit actinomycetes as a source of novel natural products [J].

Genilloud, Olga ;

Gonzalez, Ignacio ;

Salazar, Oscar ;

Martin, Jesus ;

Ruben Tormo, Jose ;

Vicente, Francisca .

JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, 2011, 38 (03) :375-389

[7] Proteomic Analysis of Global Changes in Protein Expression During Exposure of Gamma Radiation in Bacillus sp HKG 112 Isolated from Saline Soil [J].

Gupta, Anil Kumar ;

Pathak, Rajiv ;

Singh, Bharat ;

Gautam, Hemlata ;

Kumar, Ram ;

Kumar, Raj ;

Arora, Rajesh ;

Gautam, Hemant K. .

JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2011, 21 (06) :574-581

[8] Diversity and Polymorphism in AHL-Lactonase Gene (aiiA) of Bacillus [J].

Huma, Nusrat ;

Shankar, Pratap ;

Kushwah, Jyoti ;

Bhushan, Ashish ;

Joshi, Jayadev ;

Mukherjee, Tanmoy ;

Raju, Sajan C. ;

Purohit, Hemant J. ;

Kalia, Vipin Chandra .

JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2011, 21 (10) :1001-1011

[9] Quorum sensing inhibitors: An overview [J].

Kalia, Vipin Chandra .

BIOTECHNOLOGY ADVANCES, 2013, 31 (02) :224-245

[10]

Kalia Vipin Chandra, 2011, Open Microbiol J, V5, P1, DOI 10.2174/1874285801105010001

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