The effects of osmotic dehydration (OD) with or without pulsed vacuum (PV) on hot-air drying kinetics and quality attributes of cherry tomatoes were investigated. Both OD and PVOD pre-treatments were performed for 3h at 50 degrees C in 50 and 70(o) Brix sucrose solutions with a solution-to-fruit mass ratio of 4:1, and PVOD was applied for 15min before OD at atmospheric pressure. Samples were further dried at air temperature of 70 degrees C. Effective moisture diffusivity (D-eff) of osmotically dehydrated samples increased gradually while the D-eff curve of fresh samples had a plateau stage during hot air drying. Lower glass transition temperature, T-g, values of osmotically dehydrated samples indicated that they needed a lower storage temperature. Both OD and PVOD pre-treatments had advantages in shortening drying cycles and improving quality of products. Compared with air drying, osmo-air drying decreased the total drying time, color change, and hardness of dried samples by 32.26%, 18.11%, and 88.21%, respectively, and increased volume ratio and vitamin C retention rate by 72.31% and 125.82%. As compared with OD, PVOD decreased color change and hardness by 28.48% and 45.17%, increased volume ratio and vitamin C retention rate by 27.41% and 17.77%, but there was no significant difference shown in drying time. Therefore, osmotic pre-treatment can shorten the total dehydration time, and improve the general quality of dried cherry tomatoes.