CLAUDINS AND THE MODULATION OF TIGHT JUNCTION PERMEABILITY

被引：1046
作者：
Guenzel, Dorothee
Yu, Alan S. L. [1 ]
机构：
[1] Univ Kansas, Med Ctr, Kidney Inst, Kansas City, KS 66160 USA
来源：
PHYSIOLOGICAL REVIEWS | 2013年 / 93卷 / 02期
基金：
美国国家卫生研究院;
关键词：
BLOOD-BRAIN-BARRIER; GROWTH-FACTOR-BETA; INTEGRAL MEMBRANE-PROTEINS; THICK ASCENDING LIMB; NF-KAPPA-B; INTESTINAL EPITHELIAL-CELLS; TISSUE-SPECIFIC EXPRESSION; 1ST EXTRACELLULAR DOMAIN; CANINE KIDNEY-CELLS; SUBCELLULAR-LOCALIZATION;
D O I：
10.1152/physrev.00019.2012
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
Gunzel D, Yu ASL. Claudins and the Modulation of Tight Junction Permeability. Physiol Rev 93: 525-569, 2013; doi:10.1152/physrev.00019.2012.-Claudins are tight junction membrane proteins that are expressed in epithelia and endothelia and form paracellular barriers and pores that determine tight junction permeability. This review summarizes our current knowledge of this large protein family and discusses recent advances in our understanding of their structure and physiological functions.
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收藏
页码：525 / 569
页数：45
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共 429 条
  • [1] Claudins 6, 9, and 13 are developmentally expressed renal tight junction proteins
    Abuazza, Ghazala
    Becker, Amy
    Williams, Scott S.
    Chakravarty, Sumana
    Truong, Hoang-Trang
    Lin, Fangming
    Baum, Michel
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2006, 291 (06) : F1132 - F1141
  • [2] Distribution of the tight junction proteins ZO-1, occludin, and claudin-4,-8, and-12 in bladder epithelium
    Acharya, P
    Beckel, J
    Ruiz, WG
    Wang, E
    Rojas, R
    Birder, L
    Apodaca, G
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2004, 287 (02) : F305 - F318
  • [3] The plasma membrane proteins Prm1 and Fig1 ascertain fidelity of membrane fusion during yeast mating
    Aguilar, Pablo S.
    Engel, Alex
    Walter, Peter
    [J]. MOLECULAR BIOLOGY OF THE CELL, 2007, 18 (02) : 547 - 556
  • [4] Claudin-1 required for HCV virus entry has high potential for phosphorylation and O-glycosylation
    Ahmad, Waqar
    Shabbiri, Khadija
    Ijaz, Bushra
    Asad, Sultan
    Sarwar, Muhammad T.
    Gull, Sana
    Kausar, Humera
    Fouzia, Kiran
    Shahid, Imran
    Hassan, Sajida
    [J]. VIROLOGY JOURNAL, 2011, 8
  • [5] Tight junctions: Molecular architecture and function
    Aijaz, S
    Balda, MS
    Matter, K
    [J]. INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 248, 2006, 248 : 261 - 298
  • [6] Overexpression of claudin-7 decreases the paracellular Cl- conductance and increases the paracellular Na+ conductance in LLC-PK1 cells
    Alexandre, MD
    Lu, Q
    Chen, YH
    [J]. JOURNAL OF CELL SCIENCE, 2005, 118 (12) : 2683 - 2693
  • [7] The first extracellular domain of claudin-7 affects paracellular Cl- permeability
    Alexandre, Michele D.
    Jeansonne, Beverly G.
    Renegar, Randall H.
    Tatum, Rodney
    Chen, Yan-Hua
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007, 357 (01) : 87 - 91
  • [8] The Sur7 Protein Regulates Plasma Membrane Organization and Prevents Intracellular Cell Wall Growth in Candida albicans
    Alvarez, Francisco J.
    Douglas, Lois M.
    Rosebrock, Adam
    Konopka, James B.
    [J]. MOLECULAR BIOLOGY OF THE CELL, 2008, 19 (12) : 5214 - 5225
  • [9] TNFα-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, Akt and NFκB signaling
    Amasheh, Maren
    Fromm, Anja
    Krug, Susanne M.
    Amasheh, Salah
    Andres, Susanne
    Zeitz, Martin
    Fromm, Michael
    Schulzke, Joerg-Dieter
    [J]. JOURNAL OF CELL SCIENCE, 2010, 123 (23) : 4145 - 4155
  • [10] Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells
    Amasheh, S
    Meiri, N
    Gitter, AH
    Schöneberg, T
    Mankertz, J
    Schulzke, JD
    Fromm, M
    [J]. JOURNAL OF CELL SCIENCE, 2002, 115 (24) : 4969 - 4976
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