Molecular design of aquaporin-1 water channel as revealed by electron crystallography

被引：104
|
作者：
Li, HL [1 ]
Lee, S [1 ]
Jap, BK [1 ]
机构：
[1] UNIV CALIF BERKELEY,LAWRENCE BERKELEY LAB,DIV LIFE SCI,BERKELEY,CA 94720
来源：
NATURE STRUCTURAL BIOLOGY | 1997年 / 4卷 / 04期
关键词：
D O I：
10.1038/nsb0497-263
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The electron crystallographic structure of the aquaporin-1 water channel, determined at similar to 6 Angstrom, reveals that the protein has six transmembrane alpha-helices forming a trapezoid-like cylinder. There is a branched rod-like structure within the cylinder that traverses the membrane and likely contains at least one alpha-helix.
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收藏
页码：263 / 265
页数：3
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