RETRACTED: Obesity and mortality of COVID-19. Meta-analysis (Retracted Article)

被引:246
|
作者
Hussain, Abdulzahra [1 ,2 ]
Mahawar, Kamal [3 ]
Xia, Zefeng [4 ]
Yang, Wah [5 ]
EL-Hasani, Shamsi [6 ]
机构
[1] Doncaster & Bassetlaw Teaching Hosp, Doncaster, England
[2] Univ Sheffield, Sheffield, S Yorkshire, England
[3] Sunderland Royal Hosp, Dept Gen Surg, Bariatr Unit, Sunderland, England
[4] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, 1277 Jiefang Ave, Wuhan, Hubei, Peoples R China
[5] Jinan Univ, Affiliated Hosp 1, 613 Huangpu Ave West, Guangzhou, Guangdong, Peoples R China
[6] Kings Coll Hosp NHS Fdn Trust, Princess Royal Univ Hosp, Bariatr Unit, London, England
关键词
Obesity; COVID-19; World Health Organization; Mortality; Intensive care unit; Body mass index; Total body weight; INNATE IMMUNITY;
D O I
10.1016/j.orcp.2020.07.002
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Obesity is a global disease with at least 2.8 million people dying each year as a result of being overweight or obese according to the world health organization figures. This paper aims to explore the links between obesity and mortality in COVID-19. Methods: Electronic search was made for the papers studying obesity as a risk factor for mortality following COVID-19 infection. Three authors independently selected the papers and agreed for final inclusion. The outcomes were the age, gender, body mass index, severe comorbidities, respiratory support and the critical illness related mortality in COVID-19. 572 publications were identified and 42 studies were selected including one unpublished study data. Only 14 studies were selected for quantitative analysis. Results: All the primary points but the gender are significantly associated with COVID-19 mortality. The age >70, [odd ratio (OR): 0.17, CI; 95%, P-value: <0.00001], gender [OR: 0.89; CI: 95%, P-value: 0.32], BMI > 25 kg/m(2) [OR: 3.68, CI: 95%, P-value: <0.003], severe comorbidities [OR: 1.84, CI:95%, P-value: <0.00001], advanced respiratory support [OR: 6.98, CI: 95%, P-value: <0.00001], and critical illness [OR: 2.03, CI: 95%, P-value: <0.00001]. Conclusions: Patients with obesity are at high risk of mortality from COVID-19 infection. (C) 2020 Asia Oceania Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:295 / 300
页数:6
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