Enhancement Effect of Cytotoxicity Response of Silver Nanoparticles Combined with Thermotherapy on C6 Rat Glioma Cells

被引：22
|
作者：
Wang, Rui [1 ]
Chen, Chunmei [1 ]
Yang, Weizhong [1 ]
Shi, Songsheng [1 ]
Chen, Jing [1 ]
机构：
[1] Fujian Med Univ, Affiliated Union Hosp, Dept Neurosurg, Fuzhou 350001, Peoples R China
来源：
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY | 2013年 / 13卷 / 06期
关键词：
Silver Nanoparticles; Hyperthermia; Thermosensitivity; Cancer Cells; GOLD NANOPARTICLES; DNA-DAMAGE; IN-VIVO; HYPERTHERMIA; NANOSILVER; NANOCOMPOSITE; RADIOTHERAPY; APOPTOSIS; CYCLE;
D O I：
10.1166/jnn.2013.7156
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The present studies reveal that silver nanoparticles (AgNPs) can induce apoptosis and enhance radio-sensitivity on cancer cells. In this paper, we mainly investigated the effect of AgNPs on rat glionna C6 cells upon the combination treatment of hyperthermia treatment (HTT). AgNPs were synthesized by a polyol process and the mean size was 15 nm. The particles showed dose-dependent cytotoxicity on 06 cells from the experimental data. Besides, we found that heating cells could enhance the contents of cell uptake of AgNPs. From the survival curves, AgNPs showed the ability to enhance thermo-sensitivity on C6 cells. Our results revealed that AgNPs could have a potential application in enhancing effect on HTT induced killing of glioma cells.
引用
收藏
页码：3851 / 3854
页数：4
相关论文
共 50 条
  • [1] Effects of ZnO Nanoparticles on Rat Glioma C6 Cells
    Su Jing
    Yu Mingyue
    Lin Zhen
    Zhao Hang
    Liu Haiyan
    CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2017, 33 (06) : 908 - 911
  • [2] Effects of ZnO nanoparticles on rat glioma C6 cells
    Jing Su
    Mingyue Yu
    Zhen Lin
    Hang Zhao
    Haiyan Liu
    Chemical Research in Chinese Universities, 2017, 33 : 908 - 911
  • [3] Characteristics of sulfasalazine-induced cytotoxicity in C6 rat glioma cells
    Ignarro, Raffaela Silvestre
    Facchini, Gustavo
    de Melo, Daniela Rodrigues
    Pelizzaro-Rocha, Karin Juliane
    Ferreira, Carmen Verissima
    Castilho, Roger Frigerio
    Rogerio, Fabio
    NEUROSCIENCE LETTERS, 2017, 638 : 189 - 195
  • [4] Antitumoral effect of doxazosin on C6 rat glioma cells.
    Maier Gaelzer, M.
    Flores Mello, H.
    Paranhos Coelho, B.
    Hoffmann de Quadros, A.
    Bender Hoppe, J.
    Barea Guerra, M.
    Saraiva Goncalves, C.
    Usach, V.
    Setton-Avruj, P.
    Gazzana Salbego, C.
    MOLECULAR BIOLOGY OF THE CELL, 2014, 25
  • [5] Quercetin-loaded nanoparticles enhance cytotoxicity and antioxidant activity on C6 glioma cells
    Ersoz, Melike
    Erdemir, Aysegul
    Derman, Serap
    Arasoglu, Tulin
    Mansuroglu, Banu
    PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 2020, 25 (06) : 757 - 766
  • [6] Stress response of lysosomal cysteine proteinases in rat C6 glioma cells
    Xu, CS
    Fracella, F
    RichterLandsberg, C
    Rensing, L
    COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 1997, 117 (02): : 169 - 178
  • [7] Toxicity of compound A to C6 rat glioma cells
    Konat, GW
    Kofke, WA
    Miric, S
    METABOLIC BRAIN DISEASE, 2003, 18 (01) : 11 - 15
  • [8] MORPHOLOGICAL CHANGES IN RAT C6 GLIOMA CELLS
    OEY, JL
    SCHLAEGER, EJ
    KNIPPERS, R
    HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE, 1975, 356 (03): : 258 - 259
  • [9] Toxicity of Compound A to C6 Rat Glioma Cells
    Gregory W. Konat
    W. Andrew Kofke
    Slobodan Miric
    Metabolic Brain Disease, 2003, 18 : 11 - 15
  • [10] ENHANCEMENT OF RADIOSENSITIVITY BY TAMOXIFEN IN C6 GLIOMA-CELLS
    WEI, Z
    YAMADA, H
    SAKAI, N
    NIIKAWA, S
    NOZAWA, Y
    OLSON, J
    VERTOSICK, FT
    NEUROSURGERY, 1992, 31 (04) : 725 - 730
12345