Synopsis Reduction and prevention of health care-associated infections is a worldwide priority with emphasis on increasing hand hygiene compliance. Repetitive exposure to hand hygiene products and procedures is a significant factor in the development of occupational irritant hand dermatitis. Compliance has been difficult to achieve often due to skin irritation. The introduction of alcohol hand rubs has positively influenced compliance but rates remain lower than required. Genetic and environmental factors to the frequency and severity of irritant contact dermatitis have been identified. Because of the skin's role in innate immunity, maintenance of epidermal integrity is a key strategy for reducing health care-associated infections. In this review, we examine the interdependence of the two issues and the challenges of simultaneously accomplishing both goals. We emphasize research conducted among healthcare workers in their clinical settings. The factors that influence skin integrity and the challenges in meeting both goals simultaneously are explored. Cosmetic scientists have played key roles in the development of improved skin care products, and the issues present an excellent opportunity for them to provide potentially life-saving contributions to health care.
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Univ Nottingham, Queens Med Ctr, Fac Med & Hlth Sci, Nottingham NG7 2UH, EnglandUniv Nottingham, Queens Med Ctr, Fac Med & Hlth Sci, Nottingham NG7 2UH, England
Randle, J.
Clarke, M.
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Univ Nottingham, Queens Med Ctr, Fac Med & Hlth Sci, Nottingham NG7 2UH, EnglandUniv Nottingham, Queens Med Ctr, Fac Med & Hlth Sci, Nottingham NG7 2UH, England
Clarke, M.
Storr, J.
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Univ Nottingham, Queens Med Ctr, Fac Med & Hlth Sci, Nottingham NG7 2UH, EnglandUniv Nottingham, Queens Med Ctr, Fac Med & Hlth Sci, Nottingham NG7 2UH, England
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Soonchunhyang Univ, Div Infect Dis, Dept Internal Med, Seoul Hosp,Coll Med, 59 Daesagwan Ro, Seoul 04401, South KoreaSoonchunhyang Univ, Div Infect Dis, Dept Internal Med, Seoul Hosp,Coll Med, 59 Daesagwan Ro, Seoul 04401, South Korea
Park, Se Yoon
Park, Suyeon
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Soonchunhyang Univ, Seoul Hosp, Dept Biostat, Seoul, South Korea
Chung Ang Univ, Dept Appl Stat, Seoul, South KoreaSoonchunhyang Univ, Div Infect Dis, Dept Internal Med, Seoul Hosp,Coll Med, 59 Daesagwan Ro, Seoul 04401, South Korea
Park, Suyeon
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Hwang, Beom Seuk
Lee, Eunjung
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Soonchunhyang Univ, Div Infect Dis, Dept Internal Med, Seoul Hosp,Coll Med, 59 Daesagwan Ro, Seoul 04401, South KoreaSoonchunhyang Univ, Div Infect Dis, Dept Internal Med, Seoul Hosp,Coll Med, 59 Daesagwan Ro, Seoul 04401, South Korea
Lee, Eunjung
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Kim, Tae Hyong
Won, Sungho
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Seoul Natl Univ, Dept Publ Hlth Sci, Seoul 08826, South KoreaSoonchunhyang Univ, Div Infect Dis, Dept Internal Med, Seoul Hosp,Coll Med, 59 Daesagwan Ro, Seoul 04401, South Korea
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Guys & St Thomas NHS Fdn Trust, St Johns Inst Dermatol, Dept Cutaneous Allergy, London, EnglandGuys & St Thomas NHS Fdn Trust, St Johns Inst Dermatol, Dept Cutaneous Allergy, London, England
Teo, Ying X.
Lee, Shan X.
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Changi Gen Hosp, Dept Dermatol, Singapore, SingaporeGuys & St Thomas NHS Fdn Trust, St Johns Inst Dermatol, Dept Cutaneous Allergy, London, England
Lee, Shan X.
White, Ian R.
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Guys & St Thomas NHS Fdn Trust, St Johns Inst Dermatol, Dept Cutaneous Allergy, London, EnglandGuys & St Thomas NHS Fdn Trust, St Johns Inst Dermatol, Dept Cutaneous Allergy, London, England
White, Ian R.
Mcfadden, John P.
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Guys & St Thomas NHS Fdn Trust, St Johns Inst Dermatol, Dept Cutaneous Allergy, London, EnglandGuys & St Thomas NHS Fdn Trust, St Johns Inst Dermatol, Dept Cutaneous Allergy, London, England
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Univ Fed Santa Maria, Hosp Univ Santa Maria, Santa Maria, RS, BrazilUniv Fed Santa Maria, Hosp Univ Santa Maria, Santa Maria, RS, Brazil
Zottele, Caroline
Bosi de Souza Magnago, Tania Solange
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Univ Fed Santa Maria, Dept Enfermagem, Santa Maria, RS, BrazilUniv Fed Santa Maria, Hosp Univ Santa Maria, Santa Maria, RS, Brazil
Bosi de Souza Magnago, Tania Solange
dos Santos Dullius, Angela Isabel
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Univ Fed Santa Maria, Dept Estat, Santa Maria, RS, BrazilUniv Fed Santa Maria, Hosp Univ Santa Maria, Santa Maria, RS, Brazil
dos Santos Dullius, Angela Isabel
Bernat Kolankiewicz, Adriane Cristina
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Univ Reg Noroeste Estado Rio Grande do Sul, Dept Ciencias Vida, Ijui, RS, BrazilUniv Fed Santa Maria, Hosp Univ Santa Maria, Santa Maria, RS, Brazil
Bernat Kolankiewicz, Adriane Cristina
Dal Ongaro, Juliana
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Univ Fed Santa Maria, Dept Enfermagem, Santa Maria, RS, BrazilUniv Fed Santa Maria, Hosp Univ Santa Maria, Santa Maria, RS, Brazil