Getting trichy: tools and approaches to interrogating Trichomonas vaginalis in a post-genome world

被引：27

作者：

Conrad, Melissa D. ^{[1
]}

Bradic, Martina ^{[1
]}

Warring, Sally D. ^{[1
]}

Gorman, Andrew W. ^{[1
]}

Carlton, Jane M. ^{[1
]}

机构：

[1] NYU, Dept Biol, Ctr Genom & Syst Biol, New York, NY 10003 USA

来源：

TRENDS IN PARASITOLOGY | 2013年 / 29卷 / 01期

基金：

美国国家卫生研究院;

关键词：

Trichomonas vaginalis; population genetics; omics; molecular tools; evolution; METRONIDAZOLE-RESISTANT STRAINS; IN-VITRO; GIARDIA-INTESTINALIS; TRITRICHOMONAS-FETUS; GENETIC DIVERSITY; RNA VIRUS; MRP RNA; IDENTIFICATION; HYDROGENOSOMES; POLYMORPHISM;

D O I：

10.1016/j.pt.2012.10.004

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Trichomonas vaginalis is a parasite of the urogenital tract in men and women, with a worldwide presence and significant implications for global public health. T. vaginalis research entered the age of genomics with the publication of the first genome sequence in 2007, but subsequent utilization of other 'omics' technologies and methods has been slow. Here, we review some of the tools and approaches available to interrogate T. vaginalis biology, with an emphasis on recent advances and current limitations, and draw attention to areas where further efforts are needed to examine effectively the complex and intriguing biology of the parasite.

引用

页码：17 / 25

页数：9

共 85 条

[1] Prevalence and implications of multiple-strain infections [J].

Balmer, Oliver ;

Tanner, Marcel .

LANCET INFECTIOUS DISEASES, 2011, 11 (11) :868-878

[2] Virus in Trichomonas - an ultrastructural study [J].

Benchimol, M ;

Monteiro, SP ;

Chang, TH ;

Alderete, JF .

PARASITOLOGY INTERNATIONAL, 2002, 51 (03) :293-298

[3] Association Between Trichomonas vaginalis and Vaginal Bacterial Community Composition Among Reproductive-Age Women [J].

Brotman, Rebecca M. ;

Bradford, L. Latey ;

Conrad, Melissa ;

Gajer, Pawel ;

Ault, Kevin ;

Peralta, Ligia ;

Forney, Larry J. ;

Carlton, Jane M. ;

Abdo, Zaid ;

Ravel, Jacques .

SEXUALLY TRANSMITTED DISEASES, 2012, 39 (10) :807-812

[4] Tackling antibiotic resistance [J].

Bush, Karen ;

Courvalin, Patrice ;

Dantas, Gautam ;

Davies, Julian ;

Eisenstein, Barry ;

Huovinen, Pentti ;

Jacoby, George A. ;

Kishony, Roy ;

Kreiswirth, Barry N. ;

Kutter, Elizabeth ;

Lerner, Stephen A. ;

Levy, Stuart ;

Lewis, Kim ;

Lomovskaya, Olga ;

Miller, Jeffrey H. ;

Mobashery, Shahriar ;

Piddock, Laura J. V. ;

Projan, Steven ;

Thomas, Christopher M. ;

Tomasz, Alexander ;

Tulkens, Paul M. ;

Walsh, Timothy R. ;

Watson, James D. ;

Witkowski, Jan ;

Witte, Wolfgang ;

Wright, Gerry ;

Yeh, Pamela ;

Zgurskaya, Helen I. .

NATURE REVIEWS MICROBIOLOGY, 2011, 9 (12) :894-896

[5] Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis [J].

Carlton, Jane M. ;

Hirt, Robert P. ;

Silva, Joana C. ;

Delcher, Arthur L. ;

Schatz, Michael ;

Zhao, Qi ;

Wortman, Jennifer R. ;

Bidwell, Shelby L. ;

Alsmark, U. Cecilia M. ;

Besteiro, Sebastien ;

Sicheritz-Ponten, Thomas ;

Noel, Christophe J. ;

Dacks, Joel B. ;

Foster, Peter G. ;

Simillion, Cedric ;

Van de Peer, Yves ;

Miranda-Saavedra, Diego ;

Barton, Geoffrey J. ;

Westrop, Gareth D. ;

Mueller, Sylke ;

Dessi, Daniele ;

Fiori, Pier Luigi ;

Ren, Qinghu ;

Paulsen, Ian ;

Zhang, Hanbang ;

Bastida-Corcuera, Felix D. ;

Simoes-Barbosa, Augusto ;

Brown, Mark T. ;

Hayes, Richard D. ;

Mukherjee, Mandira ;

Okumura, Cheryl Y. ;

Schneider, Rachel ;

Smith, Alias J. ;

Vanacova, Stepanka ;

Villalvazo, Maria ;

Haas, Brian J. ;

Pertea, Mihaela ;

Feldblyum, Tamara V. ;

Utterback, Terry R. ;

Shu, Chung-Li ;

Osoegawa, Kazutoyo ;

de Jong, Pieter J. ;

Hrdy, Ivan ;

Horvathova, Lenka ;

Zubacova, Zuzana ;

Dolezal, Pavel ;

Malik, Shehre-Banoo ;

Logsdon, John M., Jr. ;

Henze, Katrin ;

Gupta, Arti .

SCIENCE, 2007, 315 (5809) :207-212

[6] Critical Taxonomic Revision of Parabasalids with Description of one New Genus and three New Species [J].

Cepicka, Ivan ;

Hampl, Vladimir ;

Kulda, Jaroslav .

PROTIST, 2010, 161 (03) :400-433

[7] Characterization of RNase MRP RNA and novel snoRNAs from Giardia intestinalis and Trichomonas vaginalis [J].

Chen, Xiaowei S. ;

Penny, David ;

Collins, Lesley J. .

BMC GENOMICS, 2011, 12

[8] High Throughput Genome-Wide Survey of Small RNAs from the Parasitic Protists Giardia intestinalis and Trichomonas vaginalis [J].

Chen, Xiaowei ;

Collins, Lesley J. ;

Biggs, Patrick J. ;

Penny, David .

GENOME BIOLOGY AND EVOLUTION, 2009, 1 :165-175

[9] Murine Models of Vaginal Trichomonad Infections [J].

Cobo, Eduardo R. ;

Eckmann, Lars ;

Corbeil, Lynette B. .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2011, 85 (04) :667-673

[10] Microsatellite polymorphism in the sexually transmitted human pathogen Trichomonas vaginalis indicates a genetically diverse parasite [J].

Conrad, Melissa ;

Zubacova, Zuzana ;

Dunn, Linda A. ;

Upcroft, Jacqui ;

Sullivan, Steven A. ;

Tachezy, Jan ;

Carlton, Jane M. .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2011, 175 (01) :30-38

← 1 2 3 4 5 6 7 8 9 →