Effect of caloric restriction on depression

被引:44
|
作者
Manchishi, Stephen Malunga [1 ,2 ]
Cui, Ran Ji [1 ]
Zou, Xiao Han [1 ]
Cheng, Zi Qian [1 ]
Li, Bing Jin [1 ]
机构
[1] Jilin Univ, Hosp 2, Jilin Prov Key Lab Mol & Chem Genet, Changchun, Jilin, Peoples R China
[2] Univ Cambridge, Dept Physiol, Cambridge, England
关键词
antidepressant; fasting; calorie restriction; BDNF; DIETARY RESTRICTION; NEUROTROPHIC FACTOR; HIPPOCAMPAL NEUROGENESIS; GLUCOSE-METABOLISM; BRAIN; BDNF; INCREASES; BEHAVIOR; OBESITY; STRESS;
D O I
10.1111/jcmm.13418
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Recently, most of evidence shows that caloric restriction could induce antidepressant-like effects in animal model of depression. Based on studies of the brain-gut axis, some signal pathways were common between the control of caloric restriction and depression. However, the specific mechanism of the antidepressant-like effects induced by caloric restriction remains unclear. Therefore, in this article, we summarized clinical and experimental studies of caloric restriction on depression. This review may provide a new therapeutic strategy for depression.
引用
收藏
页码:2528 / 2535
页数:8
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