Aldol-cyclization reaction sequence for the synthesis of tetrahydrofurans

被引：43

作者：

Calter, MA

Sugathapala, PM

Zhu, C

机构：

[1] Department of Chemistry, Virginia Tech., Blacksburg

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 22期

关键词：

D O I：

10.1016/S0040-4039(97)00766-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The aldol reactions of alpha-diazo-beta-ketoesters with a variety of aldehydes produced adducts which underwent Rh(II)-catalyzed O-H insertion reaction to yield highly substituted tetrahydrofurans. Alkylation and decarboxylation of these tetrahydrofurans formed a wide variety of tetrahydrofuran structures. (C) 1997 Elsevier Science Ltd.

引用

页码：3837 / 3840

页数：4

共 12 条

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