A rapid prototyping method for polymer microfluidics with fixed aspect ratio and 3D tapered channels

被引:27
作者
Browne, Andrew W. [1 ,2 ]
Rust, Michael J. [1 ]
Jung, WooSeok [1 ]
Lee, Se Hwan [1 ]
Ahn, Chong H. [1 ]
机构
[1] Univ Cincinnati, Dept Elect & Comp Engn, Microsyst & BioMEMS Lab, Cincinnati, OH 45221 USA
[2] Univ Cincinnati, Coll Med, Phys Scientist Training Program, Cincinnati, OH 45267 USA
关键词
ON-A-CHIP; FABRICATION; SYSTEMS; DEVICES; MASTERS;
D O I
10.1039/b903755a
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
In this work, a new method of rapidly fabricating thermopolymer and elastomer microfluidic channels has been developed and characterized for production of microfluidics with fixed aspect ratio and 3D tapered channels. A unique way to attain a desired channel depth by simply altering channel width is demonstrated. This rapid prototyping method is compatible with replication methods such as injection molding, hot embossing and elastomer casting and offers the ability to fabricate multiple channel depths (5 mu m - 1 mm) simultaneously in a single lithographic step. This method yields facile fabrication of 3-dimensionally tapered channels and polymer lab chips.
引用
收藏
页码:2941 / 2946
页数:6
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