Relevance of 10-min delayed recall in dementia screening

被引：18

作者：

de Rotrou, J. ^{[1
]}

Battal-Merlet, L. ^{[1
]}

Wenisch, E. ^{[1
]}

Chausson, C. ^{[1
]}

Bizet, E. ^{[1
]}

Dray, F. ^{[1
]}

Lenoir, H. ^{[1
]}

Rigaud, A. -S. ^{[1
]}

Hanon, O. ^{[1
]}

机构：

[1] Hop Broca, Dept Geriatr, F-75013 Paris, France

来源：

EUROPEAN JOURNAL OF NEUROLOGY | 2007年 / 14卷 / 02期

关键词：

dementia; screening; neuropsychological test; delayed recall; memory impairment; Memory Impairment Screen;

D O I：

10.1111/j.1468-1331.2006.01578.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Within the context of early diagnosis of Alzheimer's disease (AD), there is a growing interest in neuropsychological screening tests. Amongst these tests, we focused on the largely used Memory Impairment Screen (MIS). The objective of the present work was to show that adding a 10-min delayed recall to the MIS, improves the test psychometric characteristics in order to detect dementia in the earliest stages. A prospective study was carried out on a cohort of 270 consecutive elderly ambulatory subjects attending the Broca Hospital Memory Clinic: normal controls (n = 67), mild cognitive impairment subjects (n = 98) and mildly demented patients [n = 105, Mini Mental State Examination (MMSE) = 23 +/- 4]. This study consisted in testing the advantage of the 10-min delayed recall entitled MIS-D compared with the MIS. At a cut-off score of 6, the MIS-D revealed satisfying psychometric characteristics with a sensitivity of 81% and a specificity of 91%, whilst the MIS alone indicated a sensitivity of 60% and a specificity of 88% in detecting dementia. In demented patients with MMSE score >= 26, MIS-D properties still remained satisfying (sensitivity: 75%, specificity: 92%). MIS-D is a more relevant screening test than MIS alone at very early stages of dementia.

引用

页码：144 / 149

页数：6

共 29 条

[1] Screening for dementia with the memory impairment screen [J].