CANNABIS USE IN PERSONS WITH TRAUMATIC SPINAL CORD INJURY IN DENMARK

被引:17
作者
Andresen, Sven R. [1 ]
Biering-Sorensen, Fin [2 ]
Hagen, Ellen Merete [1 ,3 ,4 ]
Nielsen, Jurgen F. [5 ]
Bach, Flemming W. [6 ]
Finnerup, Nanna B. [7 ]
机构
[1] Reg Hosp Viborg, Dept Neurol, Spinal Cord Injury Ctr Western Denmark, Heibergs Alle 4, DK-8800 Viborg, Denmark
[2] Univ Copenhagen, Rigshosp, Clin Spinal Cord Injuries, Copenhagen, Denmark
[3] Univ Bergen, Dept Clin Med, Bergen, Norway
[4] UCL, Natl Hosp Neurol & Neurosurg, Auton Unit, Queen Sq, London, England
[5] Hammel Neurorehabil & Res Ctr, Hammel, Denmark
[6] Aarhus Univ Hosp, Dept Neurol, Aarhus, Denmark
[7] Aarhus Univ, Dept Clin Med, Danish Pain Res Ctr, Aarhus, Denmark
关键词
spinal cord injury; traumatic; pain; spasticity; cannabis; survey; QUALITY-OF-LIFE; NEUROPATHIC PAIN; DOUBLE-BLIND; PREDICTORS; SPASTICITY; ALCOHOL;
D O I
10.2340/16501977-2105
中图分类号
R49 [康复医学];
学科分类号
100215 ;
摘要
Objective: To evaluate recreational and medical cannabis use in individuals with traumatic spinal cord injury, including reasons and predictors for use, perceived benefits and negative consequences. DESIGN:Cross-sectional survey in Denmark. Methods: A 35-item questionnaire was sent to 1,101 patients with spinal cord injury who had been in contact with a rehabilitation centre between 1990 and 2012. Results: A total of 537 participants completed the questionnaire. Of these, 36% had tried cannabis at least once and 9% were current users. Of current users, 79% had started to use cannabis before their spinal cord injury. The main reason for use was pleasure, but 65% used cannabis partly for spinal cord injury-related consequences and 59% reported at least good effect on pain and spasticity. Negative consequences of use were primarily inertia and feeling quiet/subdued. Lower age, living in rural areas/larger cities, tobacco-smoking, high alcohol intake and higher muscle stiffness were significantly associated with cannabis use. Those who had never tried cannabis reported that they would mainly use cannabis to alleviate pain and spasticity if it were legalized. Conclusion:Cannabis use is more frequent among individuals with spinal cord injury in Denmark than among the general population. High muscle stiffness and various demographic characteristics (lower age, living in rural areas/larger cities, tobacco-smoking and high alcohol intake) were associated with cannabis use. Most participants had started using cannabis before their spinal cord injury. There was considerable overlap between recreational and disability-related use.
引用
收藏
页码:152 / 160
页数:9
相关论文
共 41 条
[1]   Pain, spasticity and quality of life in individuals with traumatic spinal cord injury in Denmark [J].
Andresen, S. R. ;
Biering-Sorensen, F. ;
Hagen, E. M. ;
Nielsen, J. F. ;
Bach, F. W. ;
Finnerup, N. B. .
SPINAL CORD, 2016, 54 (11) :973-979
[2]  
[Anonymous], 2011, WOM MEN, P1
[3]   Barriers to access to medical cannabis for Canadians living with HIV/AIDS [J].
Belle-Isle, L. ;
Hathaway, A. .
AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV, 2007, 19 (04) :500-506
[4]   Spasticity-assessment: a review [J].
Biering-Sorensen, F. ;
Nielsen, J. B. ;
Klinge, K. .
SPINAL CORD, 2006, 44 (12) :708-722
[5]   Optimizing the Management of Disabling Spasticity Following Spinal Cord Damage: The Ability Network-An International Initiative [J].
Burns, Anthony Scott ;
Lanig, Indira ;
Grabljevec, Klemen ;
New, Peter Wayne ;
Bensmail, Djamel ;
Ertzgaard, Per ;
Nene, Anand Vishwanath .
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION, 2016, 97 (12) :2222-2228
[6]   Treatments for chronic pain in persons with spinal cord injury: A survey study [J].
Cardenas, Diana D. ;
Jensen, Mark P. .
JOURNAL OF SPINAL CORD MEDICINE, 2006, 29 (02) :109-117
[7]   International Spinal Cord Injury Quality of Life Basic Data Set [J].
Charlifue, S. ;
Post, M. W. ;
Biering-Sorensen, F. ;
Catz, A. ;
Dijkers, M. ;
Geyh, S. ;
Horsewell, J. ;
Noonan, V. ;
Noreau, L. ;
Tate, D. ;
Sinnott, K. A. .
SPINAL CORD, 2012, 50 (09) :672-675
[8]   Cannabis use in patients with multiple sclerosis [J].
Chong, M. S. ;
Wolff, K. ;
Wise, K. ;
Tanton, C. ;
Winstock, A. ;
Silber, E. .
MULTIPLE SCLEROSIS JOURNAL, 2006, 12 (05) :646-651
[9]   Patterns of cannabis use among patients with multiple sclerosis [J].
Clark, AJ ;
Ware, MA ;
Yazer, E ;
Murray, TJ ;
Lynch, ME .
NEUROLOGY, 2004, 62 (11) :2098-2100
[10]   The local antinociceptive effects of paracetamol in neuropathic pain are mediated by cannabinoid receptors [J].
Dania, Melina ;
Guindon, Josee ;
Lambert, Chantal ;
Beaulieu, Pierre .
EUROPEAN JOURNAL OF PHARMACOLOGY, 2007, 573 (1-3) :214-215