Single-molecule force spectroscopy on Bombyx mori silk fibroin by atomic force microscopy

被引：49
|
作者：
Zhang, WK
Xu, QB
Zou, S
Li, HB
Xu, WQ
Zhang, X [1 ]
Shao, ZZ
Kudera, M
Gaub, HE
机构：
[1] Jilin Univ, Key Lab Supramol Struct & Spect, Changchun 130023, Peoples R China
[2] Jilin Univ, Dept Chem, Changchun 130023, Peoples R China
[3] Fudan Univ, Dept Macromol Sci, Shanghai 200433, Peoples R China
[4] Fudan Univ, Lab Mol Engn Polymers, Shanghai 200433, Peoples R China
[5] Univ Munich, Lehrstuhl Angew Phys, D-80799 Munich, Germany
来源：
LANGMUIR | 2000年 / 16卷 / 09期
关键词：
D O I：
10.1021/la991230y
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new atomic force microscopy (AFM)-based technique, single-molecule force spectroscopy (SMFS), was used to study the nanomechanics of Bombyx mori silk fibroin. Three types of force-extension curves were found in the system. A modified freely jointed chain (MFJC) model can fit two of the three types well, but the fit parameters are different. The third type of force curve, in which there exists a plateau, cannot be modeled by MFJC. These results may show that there are three kinds of conformations in the silk fibroin system and SMFS can "distinguish" different conformations of the polymer chains.
引用
收藏
页码：4305 / 4308
页数：4
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