Two New ent-Labdane Diterpenes from the Roots of Euphorbia yinshanica

被引：3
作者：
Zhang, Ben-Yin [1 ,2 ]
Yin, Heng-Xia [1 ]
Zhang, De-Jun [1 ,2 ]
机构：
[1] Qinghai Univ, State Key Lab Plateau Ecol & Agr, Xining 810008, Peoples R China
[2] Qinghai Univ, Coll Ecoenvironm Engn, Xining 810008, Peoples R China
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2017年 / 53卷 / 02期
基金：
中国国家自然科学基金;
关键词：
PLATYCLADUS-ORIENTALIS; CONSTITUENTS;
D O I：
10.1007/s10600-017-1973-8
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Two new ent-labdane diterpenes, ent-3 alpha,16-dihydroxylabda-8(17),12(E),14-triene (1) and ent-14(S),15-dihydroxylabda-8(17)-12(E)-dien-18-oic acid (2), were isolated from the roots of Euphorbia yinshanica. Their structures were elucidated on the basis of spectroscopic methods including HR-ESI-MS and 1D and 2D NMR. The cytotoxic activities against five tumor cell lines was also evaluated, but there was no significant activity.
引用
收藏
页码：295 / 298
页数：4
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