Arterial stiffness: Methods of measurement, physiologic determinants and prediction of cardiovascular outcomes

被引:71
作者
Sakuragi, Satoru [1 ]
Abhayaratna, Walter P. [1 ,2 ]
机构
[1] Canberra Hosp, Acad Unit Internal Med, Canberra, ACT 2606, Australia
[2] Australian Natl Univ, Coll Med Biol & Environm, Canberra, ACT, Australia
关键词
Arterial stiffness; Measurement; Determinants; Cardiovascular outcomes; PULSE-WAVE VELOCITY; BRACHIAL BLOOD-PRESSURE; CORONARY-HEART-DISEASE; STAGE RENAL-FAILURE; AORTIC STIFFNESS; AUGMENTATION INDEX; ESSENTIAL-HYPERTENSION; INDEPENDENT PREDICTOR; HEALTHY-MEN; SYSTEMIC INFLAMMATION;
D O I
10.1016/j.ijcard.2009.04.027
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Arterial stiffness has been shown to be a potent and independent predictor of cardiovascular risk. In this review, we outline methods for the measurement of arterial stiffness, describe the physiological mechanisms that underpin the utility of arterial stiffness as an integrative marker of cardiovascular disease, and detail the evidence examining the value of arterial stiffness for prediction of adverse cardiovascular events and mortality. The extent to which arterial stiffness may be modified by medical and lifestyle therapy is reviewed. (C) 2009 Published by Elsevier Ireland Ltd.
引用
收藏
页码:112 / 118
页数:7
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