Organophosphate effects on antioxidant system of carp (Cyprinus carpio) and catfish (Ictalurus nebulosus)

被引：160

作者：

Hai, DQ ^{[1
]}

Varga, SI ^{[1
]}

Matkovics, B ^{[1
]}

机构：

[1] ATTILA JOZSEF UNIV,BIOL ISOTOPE LAB,SZEGED,HUNGARY

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY | 1997年 / 117卷 / 01期

基金：

匈牙利科学研究基金会;

关键词：

fishes; organophosphate; oxygen radical changes; pro-; antioxidant system;

D O I：

10.1016/S0742-8413(96)00234-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The effect of the organophosphate insecticide Dichlorvos on antioxidant enzymes and other oxidative and redox parameters of carp (Cyprinus carpio L.) and catfish (Ictalurus nebulosus) were studied. Changes in superoxide dismutase, catalase, glutathione peroxidase, and in the case of carp acetylcholinesterase activities were studied in tissue homogenates. Other parameters studied: changes of lipid peroxidation, reduced glutathione and the amounts of two radicals, superoxide and hydroxyl radicals are compared. Our results showed that the organophosphate tested, besides its inhibitory effect on acetylcholinesterase-or together with it-induces changes characteristic of ''oxidative stress.'' (C) Elsevier Science Inc.

引用

页码：83 / 88

页数：6

共 21 条

[1]

AMAL AR, 1985, COMP BIOCH PHYSL C, V81, P395

[2] SUPEROXIDE DISMUTASE - IMPROVED ASSAYS AND AN ASSAY APPLICABLE TO ACRYLAMIDE GELS [J].