Anti-diabetic and hypoglycaemic effects of Momordica charantia (bitter melon): a mini review

被引：143

作者：

Leung, Lawrence ^{[1
]}

Birtwhistle, Richard ^{[1
]}

Kotecha, Jyoti ^{[1
]}

Hannah, Susan ^{[1
]}

Cuthbertson, Sharon ^{[1
]}

机构：

[1] Queens Univ, Ctr Studies Primary Care, Dept Family Med, Kingston, ON K7L 5E9, Canada

来源：

BRITISH JOURNAL OF NUTRITION | 2009年 / 102卷 / 12期

关键词：

Momordica charantia; Hyoglycaemic agents; Diabetes mellitus; Complementary and alternative medicine; GLUCOSE-TOLERANCE; POSTPRANDIAL HYPERGLYCEMIA; DIABETES-MELLITUS; GLYCEMIC CONTROL; FRUIT PULP; INSULIN; EXTRACT; PLANT; RATS; TRITERPENOIDS;

D O I：

10.1017/S0007114509992054

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

It has been estimated that up to one-third of patients with diabetes mellitus use some form of complementary and alternative medicine. Momordica charantia (bitter melon) is a popular fruit used for the treatment of diabetes and related conditions amongst the indigenous populations of Asia, South America, India and East Africa. Abundant pre-clinical studies have documented the anti-diabetic and hypoglycaemic effects of M. charantia through various postulated mechanisms. However, clinical trial data with human Subjects are limited and flawed by poor study design and low statistical power. The present article reviews the clinical data regarding the anti-diabetic potentials of M. charantia and calls for better-designed clinical trials to further elucidate its possible therapeutic effects.

引用

页码：1703 / 1708

页数：6

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