Comparison of chemical constituents of Chamomilla recutita (L.) Rauschert essential oil and its anti-chemotactic activity

被引：31

作者：

Marinho Presibella, Mayra ^{[1
]}

De Biaggi Villas-Boas, Larissa ^{[1
]}

Morais da Silva Belletti, Klezia ^{[1
]}

Aimbire de Moraes Santos, Cid ^{[1
]}

Maria Weffort-Santos, Almeriane ^{[1
]}

机构：

[1] Univ Fed Parana, Programa Pos Gras Ciencias Farmaceut, BR-80210170 Curitiba, Parana, Brazil

来源：

BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY | 2006年 / 49卷 / 05期

关键词：

Chamomilla recutita; Asteraceae; essential oil; chemotaxis; bisabolol oxide;

D O I：

10.1590/S1516-89132006000600005

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Several essential oil samples from dried flower-heads of Chamomilla recutita (L.) Rauschert, grown and commercially available around Curitiba metropolitan area, South of Brazil, were analyzed by GC-MS and the chemical constituents were compared with an Egyptian sample obtained under similar conditions and used as a control. The local grown herbs showed levels of essential oil below the standards recommended by the Brazilian Pharmacopoeia. Also, differences in their composition as well as in the quantity of several components were found such as the unexpected inversion of the relative constitution of the A and B alpha-bisabolol oxides. Of particular interest was the striking effect of the chamomile extracts upon human leukocyte chemotaxis, a biological anti-inflammatory activity not reported before, in which cell migration was in vitro inhibited at the same level as showed by dexamethasone.

引用

页码：717 / 724

页数：8

共 44 条

[1] PHARMACOLOGICAL INVESTIGATIONS WITH COMPOUNDS OF CHAMOMILE .5. INVESTIGATIONS ON THE SPASMOLYTIC EFFECT OF COMPOUNDS OF CHAMOMILE AND KAMILLOSAN ON THE ISOLATED GUINEA-PIG ILEUM [J].