Moringa Oleifera: A Review of Its Occurrence, Pharmacological Importance and Oxidative Stress

被引:21
|
作者
Ercan, Kenan [1 ]
Gecesefa, Omer Faruk [1 ]
Taysi, Muhammed Enes [2 ]
Ali, Omeed Akbar Ali [3 ]
Taysi, Seyithan [4 ]
机构
[1] Gaziantep Univ, Nurdagi Vocat Sch, Gaziantep, Turkey
[2] Gaziantep Univ, Med Sch, Gaziantep, Turkey
[3] Gaziantep Univ, Dept Biochem & Technol, Gaziantep, Turkey
[4] Gaziantep Univ, Dept Med Biochem, Med Sch, Gaziantep, Turkey
关键词
Moringa oleifera; nitrosative stress; oxidative stress; free radicals; antioxidants; ACID PHENETHYL ESTER; LIPID-PEROXIDATION; ANTIOXIDANT ACTIVITY; FREE-RADICALS; NITRIC-OXIDE; LEAF EXTRACT; VITAMIN-E; HEPATOCELLULAR-CARCINOMA; TISSUE-INJURY; CELLS;
D O I
10.2174/1389557520999200728162453
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Oxidative/nitrosative stress can be caused by excessive production of ROS and RNS with metabolic reactions that change the balance in favor of oxidants in cases where oxidants increase and antioxidants decrease in organisms using oxygen. ROS and RNS react with several biological macromolecules in cells, such as carbohydrates, nucleic acids, lipids, and proteins, and alter their functions. Some natural antioxidants are constantly being researched for their benefits in terms of human health, which can strengthen the body's antioxidant defense system and have the potential to scavenger free radicals. It is a well-known and practical strategy to prevent and / or treat diseases due to the consumption of more suitable fruits, herbs, spices and vegetables, and the presence of bioactive antioxidant compounds. Moringa oleifera, a new and important one of these plants, has a wide range of bioactive compounds that can be obtained in different herbal structures such as leaves, seeds, stems and shells. It consists of bioactive molecules, such as phenolic compounds, fats, fatty acids, carbohydrates, proteins, functional peptides, vitamins, minerals and essential amino acids as well as a number of glycosides and has great potential for use in various formulations in various health and food products. This review highlights the formation of MO, its importance in natural medicine, its pharmacological value, and its role as a possible anti-proliferative agent against cancer and its use in some diseases.
引用
收藏
页码:380 / 396
页数:17
相关论文
共 50 条
  • [21] Moringa oleifera Lam.: A Phytochemical and Pharmacological Overview
    Anzano, Attilio
    Ammar, Mohammad
    Papaianni, Marina
    Grauso, Laura
    Sabbah, Mohammed
    Capparelli, Rosanna
    Lanzotti, Virginia
    HORTICULTURAE, 2021, 7 (10)
  • [22] Nutraceutical or Pharmacological Potential of Moringa oleifera Lam.
    Kou, Xianjuan
    Li, Biao
    Olayanju, Julia B.
    Drake, Justin M.
    Chen, Ning
    NUTRIENTS, 2018, 10 (03)
  • [23] A comprehensive review of the phytochemicals, health benefits, pharmacological safety and medicinal prospects of Moringa oleifera
    Camilleri, Emma
    Blundell, Renald
    HELIYON, 2024, 10 (06)
  • [24] Moringa oleifera: An Updated Comprehensive Review of Its Pharmacological Activities, Ethnomedicinal, Phytopharmaceutical Formulation, Clinical, Phytochemical, and Toxicological Aspects
    Pareek, Ashutosh
    Pant, Malvika
    Gupta, Madan Mohan
    Kashania, Pushpa
    Ratan, Yashumati
    Jain, Vivek
    Pareek, Aaushi
    Chuturgoon, Anil A. A.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (03)
  • [25] Syringic acid (SA) - A Review of Its Occurrence, Biosynthesis, Pharmacological and Industrial Importance
    Cheemanapalli, Srinivasulu
    Mopuri, Ramgopal
    Golla, Ramanjaneyulu
    Anuradha, C. M.
    Chitta, Suresh Kumar
    BIOMEDICINE & PHARMACOTHERAPY, 2018, 108 : 547 - 557
  • [26] Review of the Safety and Efficacy of Moringa oleifera
    Stohs, Sidney J.
    Hartman, Michael J.
    PHYTOTHERAPY RESEARCH, 2015, 29 (06) : 796 - 804
  • [27] Moringa oleifera in a modern time: A comprehensive review of its nutritional and bioactive composition as a natural solution for managing diabetes mellitus by reducing oxidative stress and inflammation
    Gul, Palwasha
    Khan, Jabir
    Li, Qingyun
    Liu, Kunlun
    FOOD RESEARCH INTERNATIONAL, 2025, 201
  • [28] Moringa oleifera and inflammation: a mini-review of its effects and mechanisms
    Ray, S. J.
    Wolf, T. J.
    Mowa, C. N.
    I INTERNATIONAL SYMPOSIUM ON MORINGA, 2017, 1158 : 317 - 329
  • [29] Effects of Moringa oleifera L. Herb and its extract on indomethacin-induced gastric oxidative stress in rats
    Wahba, Hany M. A.
    Shelbaya, Lobna A.
    BIOSCIENCE RESEARCH, 2018, 15 (03): : 1917 - 1924
  • [30] Moringa oleifera: a review of the medicinal potential
    Fahey, J. W.
    I INTERNATIONAL SYMPOSIUM ON MORINGA, 2017, 1158 : 209 - 224