Some Effects of Different Constitutive Laws on FSI Simulation for the Mitral Valve

被引：13
作者：
Cai, Li [1 ]
Wang, Ying [1 ]
Gao, Hao [2 ]
Mai, Xingshuang [3 ]
Zhu, Guangyu [4 ]
Zhang, Ruihang [1 ]
Shen, Xiaoqin [5 ]
Luo, Xiaoyu [2 ]
机构：
[1] Northwestern Polytech Univ, NPU UoG Int Cooperat Lab Computat & Applicat Card, Xian 710129, Shaanxi, Peoples R China
[2] Univ Glasgow, Sch Math & Stat, Glasgow G12 8QQ, Lanark, Scotland
[3] Chongqing Univ, Bioengn Coll, Chongqing 400030, Peoples R China
[4] Xi An Jiao Tong Univ, Sch Energy & Power Engn, Xian 710049, Shaanxi, Peoples R China
[5] Xian Univ Technol, Sch Sci, Xian 710048, Shaanxi, Peoples R China
来源：
SCIENTIFIC REPORTS | 2019年 / 9卷 / 1期
基金：
中国国家自然科学基金; 英国工程与自然科学研究理事会;
关键词：
FINITE-ELEMENT-ANALYSIS; MECHANICAL-PROPERTIES; DYNAMIC DEFORMATION; ANNULAR DILATATION; LEFT-VENTRICLE; HEART-VALVES; MODEL; BEHAVIOR; ANNULOPLASTY; STENTLESS;
D O I：
10.1038/s41598-019-49161-6
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
In this paper, three different constitutive laws for mitral leaflets and two laws for chordae tendineae are selected to study their effects on mitral valve dynamics with fluid-structure interaction. We first fit these three mitral leaflet constitutive laws and two chordae tendineae laws with experimental data. The fluid-structure interaction is implemented in an immersed boundary framework with finite element extension for solid, that is the hybrid immersed boundary/finite element(IB/FE) method. We specifically compare the fluid-structure results of different constitutive laws since fluid-structure interaction is the physiological loading environment. This allows us to look at the peak jet velocity, the closure regurgitation volume, and the orifice area. Our numerical results show that different constitutive laws can affect mitral valve dynamics, such as the transvalvular flow rate, closure regurgitation and the orifice area, while the differences in fiber strain and stress are insignificant because all leaflet constitutive laws are fitted to the same set of experimental data. In addition, when an exponential constitutive law of chordae tendineae is used, a lower closure regurgitation flow is observed compared to that of a linear material model. In conclusion, combining numerical dynamic simulations and static experimental tests, we are able to identify suitable constitutive laws for dynamic behaviour of mitral leaflets and chordae under physiological conditions.
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页数：15
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