Perforating folliculitis associated with tumour necrosis factor-α inhibitors administered for rheumatoid arthritis

被引：17

作者：

Gilaberte, Y. ^{[1
]}

Coscojuela, C.

Vazquez, C.

Rosello, R.

Vera, J.

机构：

[1] San Jorge Gen Hosp, Dept Dermatol, Huesca, Spain

[2] San Jorge Gen Hosp, Dept Rheumatol, Huesca, Spain

[3] San Jorge Gen Hosp, Dept Pathol, Huesca, Spain

来源：

BRITISH JOURNAL OF DERMATOLOGY | 2007年 / 156卷 / 02期

关键词：

perforating folliculitis; tumour necrosis factor-alpha inhibitors;

D O I：

10.1111/j.1365-2133.2006.07598.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Perforating dermatoses are characterized by transepithelial elimination of dermal structures. We report a 61-year-old man with rheumatoid arthritis who developed a perforating folliculitis following the administration of two tumour necrosis factor (TNF)-alpha inhibitors, infliximab and etanercept. To our knowledge, no perforating disorders have been reported associated with these drugs. This report suggests, for the first time, a role for TNF-alpha in the pathogenesis of perforating folliculitis.

引用

页码：368 / 371

页数：4

共 32 条

[1] Systematic safety follow up in a cohort of 107 patients with spondyloarthropathy treated with infliximab: a new perspective on the role of host defence in the pathogenesis of the disease? [J].