Histological and Histomorphometrical Determination of the Biogradation of -Tricalcium Phosphate Granules in Maxillary Sinus Floor Augmentation: A Prospective Observational Study

被引:11
|
作者
Okada, Tsuneji [1 ]
Kanai, Toru [1 ]
Tachikawa, Noriko [1 ]
Munakata, Motohiro [2 ]
Kasugai, Shohei [1 ]
机构
[1] Tokyo Med & Dent Univ, Dent Hosp, Clin Implant Dent, Tokyo, Japan
[2] Kanagawa Dent Univ, Dept Oral & Maxillofacial Rehabil, Removable Prosthet, Yokosuka, Kanagawa, Japan
关键词
calcium phosphate; biopsy; biomaterial resorption; CBCT; AUTOGENOUS BONE; RESORPTION; ELEVATION; TISSUE; GRAFT;
D O I
10.1097/ID.0000000000000577
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Introduction:We have recently used highly pure -TCP (beta-tricalcium phosphate) as the bone grafting material to avoid highly invasive autogenous bone grafting. We evaluated the osseoconduction potential of highly pure -TCP in sinus augmentation surgery treatment.Materials and Methods:The study group comprised 13 patients who underwent maxillary sinus floor augmentation with -TCP alone. Seven patients underwent sinus augmentation and implant placement simultaneously. Six patients were treated with a staged approach. Six months after surgery, specimens were obtained from 7 patients (for lateral biopsy) and 6 patients (for vertical biopsy).Results:Histological and histomorphometrical analysis showed a mean bone proportion of 30.8% (vertical) and 12.0% (lateral) for new bone formation and good integration of the -TCP. New bone formation was lower in the lateral biopsy specimens than in the vertical.Conclusion:Highly pure -TCP is a safe bone-grafting material with superior osteoconductive properties. Histologic and radiographic examinations indicate that -TCP is slowly resorbed, which results in unresorbed graft material remaining even 6 months after the procedure, and that new bone replacement occurs slowly for approximately 1 year.
引用
收藏
页码:275 / 283
页数:9
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