The Prognostic Value of Red Blood Cell Distribution Width in Patients on Maintenance Hemodialysis

被引：16

作者：

Chen, Xiaohong ^{[1
,2
,3
]}

Shen, Bo ^{[1
,2
,3
]}

Zou, Jianzhou ^{[1
,2
,3
]}

Liu, Zhonghua ^{[1
,2
,3
]}

Lv, Wenlv ^{[1
,2
,3
]}

Cao, Xuesen ^{[1
,2
,3
]}

Yu, Jiawei ^{[1
,2
,3
]}

Nie, Yuxin ^{[1
,2
,3
]}

Xu, Jiarui ^{[1
,2
,3
]}

Wang, Li ^{[1
,2
,3
]}

Ding, Xiaoqiang ^{[1
,2
,3
]}

机构：

[1] Fudan Univ, Zhongshan Hosp, Blood Purificat Ctr, 136 Yi Xue Yuan Rd, Shanghai 200032, Peoples R China

[2] Fudan Univ, Zhongshan Hosp, Dept Nephrol, Shanghai, Peoples R China

[3] Shanghai Key Lab Kidney & Blood Purificat, Shanghai, Peoples R China

来源：

BLOOD PURIFICATION | 2016年 / 42卷 / 04期

关键词：

Red blood cell distribution width; Hemodialysis; Prognosis; LARGE COHORT; MORTALITY; MARKER; RISK; ASSOCIATION; BIOMARKERS; PREDICTOR; RDW;

D O I：

10.1159/000449421

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aims: To examine the association between red blood cell distribution width (RDW) and mortality in hemodialysis (HD) patients. Methods: Three hundred fifty six patients on HD for >3 months were enrolled and followed for 2 years. Patients were divided into 2 groups according to the median RDW value. Patient survival and risk factors for mortality were investigated. Results: The 2-year survival rate was significantly lower in the high-RDW group (>14.9%; log-rank = 10.00, p = 0.0016). RDW (hazard ratio (HR) 1.34, 95% CI 1.04-1.71, p = 0.021), hemoglobin (HR 0.98, 95% CI 0.96-1.00, p = 0.023) and albumin (HR 0.90, 95% CI 0.82-0.99, p = 0.026) were independent predictors of mortality. Receiver operating characteristic curves of RDW to predict 2-year mortality had an area under the curve of 0.6487 (95% CI 0.5714-0.7260). Conclusions: Abnormal RDW was common in HD patients and significantly related with poor outcomes in these patients. (C) 2016 S. Karger AG, Basel

引用

页码：314 / 321

页数：8

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