pH-Responsive supramolecular vesicles assembled by water-soluble pillar[5]arene and a BODIPY photosensitizer for chemo-photodynamic dual therapy

被引：132
作者：
Meng, Lu-Bo [1 ,2 ]
Zhang, Wenyi [3 ]
Li, Dongqi [1 ,2 ]
Li, Yan [3 ]
Hu, Xiao-Yu [1 ,2 ]
Wang, Leyong [1 ,2 ]
Licd, Guigen [4 ,5 ]
机构：
[1] Nanjing Univ, Key Lab Mesoscop Chem MOE, Nanjing 210093, Jiangsu, Peoples R China
[2] Nanjing Univ, Collaborat Innovat Ctr Chem Life Sci, Sch Chem & Chem Engn, Nanjing 210093, Jiangsu, Peoples R China
[3] Southeast Univ, Sch Biol Sci & Med Engn, State Key Lab Bioelect, Jiangsu Key Lab Biomat & Devices, Nanjing 210096, Jiangsu, Peoples R China
[4] Nanjing Univ, Inst Chem & BioMed Sci, Sch Chem & Chem Engn, Nanjing 210023, Jiangsu, Peoples R China
[5] Texas Tech Univ, Dept Chem & Biochem, Lubbock, TX 79409 USA
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 76期
基金：
中国国家自然科学基金; 美国国家科学基金会;
关键词：
CONTROLLABLE DRUG-RELEASE; COPOLYMER MICELLES; AMINO-ACIDS; DELIVERY; NANOPARTICLES; CANCER; DERIVATIVES; BIODISTRIBUTION; COMPLEXATION; NANOCARRIERS;
D O I：
10.1039/c5cc05785j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Supramolecular vesicles which can successfully encapsulate DOX and exhibit rapid drug release in a low-pH environment are constructed based on the host-guest interaction of water-soluble pillar[5] arene and a BODIPY derivative. They show remarkable combination of chemo- and photodynamic activities, suggesting a promising drug nanocarrier.
引用
收藏
页码：14381 / 14384
页数：4
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