Does fluorine-18 fluorodeoxyglucose metabolic imaging of tumours benefit oncology?

被引:87
作者
Brock, CS [1 ]
Meikle, SR [1 ]
Price, P [1 ]
机构
[1] ROYAL PRINCE ALFRED HOSP,PET DEPT,CAMPERDOWN,NSW 2050,AUSTRALIA
关键词
FDG; oncology; positron emission tomography;
D O I
10.1007/BF00841411
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Fluoro-deoxyglucose (FDG) is a metabolic marker, which follows the same route into cells as that of glucose, and it can be radiolabelled with fluorine-18, F-18-FDG making it suitable for imaging with positron emission tomography (PET). The fact that rapidly proliferating cells such as tumour cells accumulate F-18-FDG more avidly than those with a normal turnover rate has given rise to its potential in oncology. The rationale and previous published uses of F-18-FDG in oncology are reviewed, together with the various analysis techniques and associated methodological difficulties.
引用
收藏
页码:691 / 705
页数:15
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