Maltobionic acid accelerates recovery from iron deficiency-induced anemia in rats

被引：0

作者：

Suehiro, Daiki ^{[1
]}

Kawase, Haruka ^{[2
]}

Uehara, Sumire ^{[3
]}

Kawase, Rio ^{[3
]}

Fukami, Ken ^{[1
]}

Nakagawa, Tomoyuki ^{[2
,3
]}

Shimada, Masaya ^{[2
,3
]}

Hayakawa, Takashi ^{[2
,3
]}

机构：

[1] Sanei Sucrochem Co Ltd, Chita, Japan

[2] Gifu Univ, Grad Sch Appl Biol Sci, Gifu, Japan

[3] Gifu Univ, Grad Sch Nat Sci & Technol, Gifu, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2020年 / 84卷 / 02期

关键词：

Maltobionic acid; iron deficiency anemia; subclinical iron deficiency; iron absorption; oligosaccharide; CALCIUM MALTOBIONATE; GLASS-TRANSITION; BINDING-CAPACITY; ABSORPTION; FRUCTOOLIGOSACCHARIDES; PREVALENCE; MECHANISMS; WOMEN; HEME;

D O I：

10.1080/09168451.2019.1676694

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In experiments 1 and 2, effect of ingestion of maltobionic acid calcium salt (MBCa) on recovery of rats from a latent iron deficiency and from iron deficiency anemia was examined, respectively. After grouping rats into control and iron-deficiency groups, a latent iron deficiency or iron-deficiency anemia was induced in the latter group. And recovery from these states by MBCa containing diets (0%, 3%, and 6% MBCa in diet, classified into MBCa-0, MBCa-3, and MBCa-6 groups) was compared for convalescence period in light of iron sufficient control group. In experiment 1, MBCa ingestion significantly increased the iron concentration in the serum and liver, and promoted recovery from a latent iron deficiency. In experiment 2, hemoglobin and hematocrit levels increased significantly with MBCa intake, and recovery from iron-deficiency anemia was promoted. MBCa effectively promoted the recovery of rats from a subclinical iron deficiency and iron-deficiency anemia.

引用

页码：393 / 401

页数：9

共 31 条

[1] Iron-deficiency anemia in infancy and poorer cognitive inhibitory control at age 10 years [J].