Benzotetramisole: A remarkably enantioselective acyl transfer catalyst

被引：335

作者：

Birman, VB ^{[1
]}

Li, XM ^{[1
]}

机构：

[1] Washington Univ, Dept Chem, St Louis, MO 63130 USA

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 07期

关键词：

D O I：

10.1021/ol060065s

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A commercially available pharmaceutical, tetramisole, was found to be a competent enantioselective acylation catalyst. Its benzannellated analogue, benzotetramisole (BTM), produced outstanding enantioselectivities in kinetic resolution of secondary benzylic alcohols.

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页码：1351 / 1354

页数：4

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