ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization

被引：2512

作者：

Yu, Guangchuang ^{[1
,2
]}

Wang, Li-Gen ^{[3
]}

He, Qing-Yu ^{[1
]}

机构：

[1] Jinan Univ, Key Lab Funct Prot Res, Guangdong Higher Educ Inst, Coll Life Sci & Technol, Guangzhou 510632, Guangdong, Peoples R China

[2] Univ Hong Kong, Sch Publ Hlth, State Key Lab Emerging Infect Dis, Hong Kong, Hong Kong, Peoples R China

[3] Guangdong Informat Ctr, Guangzhou 510031, Guangdong, Peoples R China

来源：

BIOINFORMATICS | 2015年 / 31卷 / 14期

基金：

中国国家自然科学基金;

关键词：

BIOCONDUCTOR;

D O I：

10.1093/bioinformatics/btv145

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

ChIPseeker is an R package for annotating ChIP-seq data analysis. It supports annotating ChIP peaks and provides functions to visualize ChIP peaks coverage over chromosomes and profiles of peaks binding to TSS regions. Comparison of ChIP peak profiles and annotation are also supported. Moreover, it supports evaluating significant overlap among ChIP-seq datasets. Currently, ChIPseeker contains 15 000 bed file information from GEO database. These datasets can be downloaded and compare with user's own data to explore significant overlap datasets for inferring co-regulation or transcription factor complex for further investigation.

引用

收藏

页码：2382 / 2383

页数：2

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