Integration of Artificial Intelligence and CRISPR/Cas9 System for Vaccine Design

被引:10
作者
Maserat, Elham [1 ]
机构
[1] Tarbiat Modares Univ, Fac Med Sci, Dept Med Informat, Tehran 1411713116, Iran
关键词
CRISPR/Cas9; artificial intelligence; vaccine; knowledge discovery; prediction;
D O I
10.1177/11769351221140102
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The CRISPR/Cas9 system offers a new approach to genome editing and cancer treatment. This approach is able to detect drug targets and genomic analysis of cancer. The use of artificial intelligence (AI) capacity to edit genomes through CRISPR/Cas9 enables modification of gene mutations, molecular simulation. AI approaches include knowledge discovery approaches, antigen and epitope prediction approaches, and agent based-model approaches. These methods in combination with CRISPR/Cas9 can be used in vaccine design.
引用
收藏
页数:2
相关论文
共 8 条
[1]  
Akbari P., 2019, ARCH BREAST CANC, V6, P1
[2]   The Problem of Prediction in Artificial Intelligence and Synthetic Biology [J].
Bianchini, Francesco .
COMPLEX SYSTEMS, 2018, 27 (03) :249-265
[3]   Comparison of Open-Source Reverse Vaccinology Programs for Bacterial Vaccine Antigen Discovery [J].
Dalsass, Mattia ;
Brozzi, Alessandro ;
Medini, Duccio ;
Rappuoli, Rino .
FRONTIERS IN IMMUNOLOGY, 2019, 10
[4]   Requirements of integrated computational approach for developing personalized cancer vaccines [J].
Maserat, Elham ;
Nasiri Hooshmand, Mohaddeseh .
HUMAN VACCINES & IMMUNOTHERAPEUTICS, 2021, 17 (12) :5573-5574
[5]  
Nayarisseri A., 2019, INT C MULTIDISCIPLIN
[6]   The combination of artificial intelligence and systems biology for intelligent vaccine design [J].
Russo, Giulia ;
Reche, Pedro ;
Pennisi, Marzio ;
Pappalardo, Francesco .
EXPERT OPINION ON DRUG DISCOVERY, 2020, 15 (11) :1267-1281
[7]   Applications of the CRISPR-Cas9 system in cancer biology [J].
Sanchez-Rivera, Francisco J. ;
Jacks, Tyler .
NATURE REVIEWS CANCER, 2015, 15 (07) :387-395
[8]   Current applications and future perspective of CRISPR/Cas9 gene editing in cancer [J].
Wang, Si-Wei ;
Gao, Chao ;
Zheng, Yi-Min ;
Yi, Li ;
Lu, Jia-Cheng ;
Huang, Xiao-Yong ;
Cai, Jia-Bin ;
Zhang, Peng-Fei ;
Cui, Yue-Hong ;
Ke, Ai-Wu .
MOLECULAR CANCER, 2022, 21 (01)