Apoptosis - Stabbed in the BAX

被引:47
作者
Green, Douglas R. [1 ]
Chipuk, Jerry E. [1 ]
机构
[1] St Jude Childrens Hosp, Dept Immunol, Memphis, TN 38105 USA
关键词
D O I
10.1038/4551047a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Apoptotic cell death is an intricate and highly regulated process. To initiate apoptosis, the protein BIM binds to a hitherto unrecognized site on the BAX protein to trigger permeabilization of the outer mitochondrial membrane.
引用
收藏
页码:1047 / 1049
页数:3
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