A Novel Graphene-Grafted Gold Nanoparticles Composite for Highly Sensitive Electrochemical Biosensing

The use of affordable amendments required increasing the sensitivity and functionality of electrochemical devices is still challenging. Novel scalable, gold nanoparticles-grafted nitrogen-doped graphene nanostructured polyaniline nanocomposites were stupendously developed in this paper. The charge transfer resistance was dramatically decreased from 11 000 Omega (for bare fluorine doped tin oxide electrode) down to 115 Omega (for the nanocomposite-modified electrode). The present nanocomposites provided a superb opportunity for the design of electrochemical biosensors with extraordinary performance via enhanced analyte sensitivity for the detection of ascorbic acid (0.640 mM detection limit at signal to noise ratio = 3, and two linear ranges of 0.96-4.66 and 5.06-9.86 mM with the sensitivity of 10.44 and 28.91 mu A . mM(-1) . cm(-2), respectively), and high selectivity over electroactive components interfering species, commonly found in real serum samples.