Nanotechnology in stem cells research: advances and applications

被引：20

作者：

Deb, Kaushik Dilip ^{[2
]}

Griffith, May ^{[1
,3
,4
]}

De Muinck, Ebo ^{[5
]}

Rafat, Mehrdad ^{[1
]}

机构：

[1] Linkoping Univ, Dept Clin & Expt Med, Med IGEN Ctr, S-58185 Linkoping, Sweden

[2] DiponEd BioIntelligence LLP, Bangalore 560100, Karnataka, India

[3] Univ Ottawa, Ottawa Hlth Res Inst, Ottawa, ON K1H 8L6, Canada

[4] Univ Ottawa, Dept Cellular & Mol Med, Ottawa, ON K1H 8L6, Canada

[5] Linkoping Univ, Fac Hlth Sci, Dept Cardiovasc Med, S-58185 Linkoping, Sweden

来源：

FRONTIERS IN BIOSCIENCE-LANDMARK | 2012年 / 17卷

关键词：

Nanotechnology; Stem cells; Carbon nanotubes; Nanoparticles; Electron microscopy; Nanodiagnostics; Viral vectors; Review; CARBON NANOTUBES; QUANTUM DOTS; VECTOR; DIFFERENTIATION; DELIVERY; DNA; NANOMEDICINE; FIBROBLAST; ADENOVIRUS; EFFICIENT;

D O I：

10.2741/4016

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Human beings suffer from a myriad of disorders caused by biochemical or biophysical alteration of physiological systems leading to organ failure. For a number of these conditions, stem cells and their enormous reparative potential may be the last hope for restoring function to these failing organ or tissue systems. To harness the potential of stem cells for biotherapeutic applications, we need to work at the size scale of molecules and processes that govern stem cells fate. Nanotechnology provides us with such capacity. Therefore, effective amalgamation of nanotechnology and stem cells - medical nanoscience or nanomedicine - offers immense benefits to the human race. The aim of this paper is to discuss the role and importance of nanotechnology in stem cell research by focusing on several important areas such as stem cell visualization and imaging, genetic modifications and reprogramming by gene delivery systems, creating stem cell niche, and similar therapeutic applications.

引用

页码：1747 / 1760

页数：14

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