Supramolecular Strategy Based on Conjugated Polymers for Discrimination of Virus and Pathogens

被引：41

作者：

Bai, Haotian ^{[1
]}

Lu, Huan ^{[1
]}

Fu, Xuancheng ^{[1
]}

Zhang, Endong ^{[1
]}

Lv, Fengting ^{[1
]}

Liu, Libing ^{[1
]}

Wang, Shu ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Key Lab Organ Solids, Beijing 100910, Peoples R China

来源：

BIOMACROMOLECULES | 2018年 / 19卷 / 06期

基金：

中国国家自然科学基金;

关键词：

RESPIRATORY-SYNCYTIAL-VIRUS; ANTIBIOTIC-RESISTANCE; CHAIN-REACTION; BACTERIA; IDENTIFICATION; INFECTIONS; EMERGENCE; MECHANISM; DIAGNOSIS;

D O I：

10.1021/acs.biomac.8b00336

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A conjugated polymer-based supramolecular system is designed for discrimination of virus and microbes. The supramolecular system is composed of cationic polythiophene derivative (PT) and barrel-shaped macrocyclic molecular cucurbit[7]uril (CB[7]). Because PT and PT/CB [7] complexes possess different interaction manners toward virus and microbes, the rapid and simple discrimination of virus and microbes was realized through polymer fluorescence intensity change assisting with standard linear discriminant analysis (LDA). The supramolecular strategy would expand the idea of designing biological probes and further promote the extensive application of conjugated polymer materials in biosensor field.

引用

页码：2117 / 2122

页数：6

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