Pylorus-preserving versus standard pancreatoduodenectomy: An analysis of 45 periampullary carcinoma

To assess the adequacy of pylorus-preserving pancreatoduodenectomy (PPPD) as a definitive-surgical treatment for ampullary, or distal bile duct carcinomas, mortality, morbidity and 5-year cumulative survival by type and stage of cancer in 22 patients undergoing PPPD were compared with those of 23 patients undergoing standard pancreatoduodenectomy (SPD) in our institution. Hospital mortality and morbidity rates were 8.7%, 4% after PPPD, and 9%, 9% after SPD. In the patients with distal bile duct carcinoma, 5-year survival rates were 41% for those who had PPPD, and 22% for those who had SPD, In the patients with ampullary carcinoma, 5-years survival rates were 85% for those who had PPPD, and 28% for those who had SPD. PPPD is adequate as a definitive surgical treatment for ampullary or distal bile duct carcinomas.