Ultrahigh speed endoscopic optical coherence tomography using micromotor imaging catheter and VCSEL technology

被引：99

作者：

Tsai, Tsung-Han ^{[1
,2
]}

Potsaid, Benjamin ^{[1
,2
,3
]}

Tao, Yuankai K. ^{[1
,2
]}

Jayaraman, Vijaysekhar ^{[4
]}

Jiang, James ^{[3
]}

Heim, Peter J. S. ^{[5
]}

Kraus, Martin F. ^{[1
,2
,6
,7
]}

Zhou, Chao ^{[1
,2
]}

Hornegger, Joachim ^{[6
,7
]}

Mashimo, Hiroshi ^{[8
,9
]}

Cable, Alex E. ^{[3
]}

Fujimoto, James G. ^{[1
,2
]}

机构：

[1] MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA

[2] MIT, Elect Res Lab, Cambridge, MA 02139 USA

[3] Thorlabs Inc, Adv Imaging Grp, Newton, NJ USA

[4] Praevium Res Inc, Santa Barbara, CA USA

[5] Thorlabs Quantum Elect Inc, Jessup, MD USA

[6] Univ Erlangen Nurnberg, Pattern Recognit Lab, Nurnberg, Germany

[7] Univ Erlangen Nurnberg, Grad Sch Adv Opt Technol, Nurnberg, Germany

[8] Vet Affairs Healthcare Syst Boston, Boston, MA USA

[9] Harvard Univ, Sch Med, Boston, MA USA

来源：

BIOMEDICAL OPTICS EXPRESS | 2013年 / 4卷 / 07期

基金：

美国国家卫生研究院;

关键词：

FREQUENCY-DOMAIN REFLECTOMETRY; IN-VIVO; SWEPT-SOURCE; MODE-LOCKING; OCT; LASER; MICROSCOPY; SCANS;

D O I：

10.1364/BOE.4.001119

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We developed a micromotor based miniature catheter with an outer diameter of 3.2 mm for ultrahigh speed endoscopic swept source optical coherence tomography (OCT) using a vertical cavity surface-emitting laser (VCSEL) at a 1 MHz axial scan rate. The micromotor can rotate a micro-prism at several hundred frames per second with less than 5 V drive voltage to provide fast and stable scanning, which is not sensitive to the bending of the catheter. The side-viewing probe can be pulled back to acquire a three-dimensional (3D) data set covering a large area on the specimen. The VCSEL provides a high axial scan rate to support dense sampling under high frame rate operation. Using a high speed data acquisition system, in vivo 3D-OCT imaging in the rabbit GI tract and ex vivo imaging of a human colon specimen with 8 mu m axial resolution, 8 mu m lateral resolution and 1.2 mm depth range in tissue at a frame rate of 400 fps was demonstrated. (C) 2013 Optical Society of America

引用

页码：1119 / 1132

页数：14

共 50 条

[41] Importance of Optical Coherence Tomography and Optical Coherence Tomography Angiography in the Imaging and Differentiation of Choroidal Melanoma: A Review
Obuchowska, Iwona
Konopinska, Joanna
CANCERS, 2022, 14 (14)
[42] In vivo imaging of microvasculature using optical coherence tomography
Vakoc, B. J.
Lanning, R. M.
Tyrrell, J. A.
Padera, T. P.
Bartlett, L. A.
Stylianopoulos, T.
Munn, L. L.
Tearney, G. J.
Fukumura, D.
Jain, R. K.
Bouma, B. E.
2010 IEEE PHOTONICS SOCIETY WINTER TOPICALS MEETING SERIES, 2010, : 59 - 60
[43] High-speed optical coherence tomography imaging with a tunable HCG-VCSEL light source at the 1060nm wavelength window
Tsai, Ting-Yen
Chen, Ting-Hao
Chen, Hung-Kai
Chueh, Chuan-Bor
Ellafi, Dalila
Chase, Chris
Kuo, Hao-Chung
Tsai, Meng-Tsan
Huang, Michael C. Y.
Lee, Hsiang-Chieh
VERTICAL-CAVITY SURFACE-EMITTING LASERS XXVI, 2022, 12020
[44] High Speed, Full Range Imaging with Harmonic Detection Swept Source Optical Coherence Tomography
Huang, Chuanyong
Massick, Steven M.
Peterson, Kristen A.
Vakhtin, Andrei B.
OPTICAL COHERENCE TOMOGRAPHY AND COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICINE XIV, 2010, 7554
[45] Endoscopic optical coherence tomography device for forward imaging with broad field of view
Burkhardt, Anke
Walther, Julia
Cimalla, Peter
Mehner, Mirko
Koch, Edmund
JOURNAL OF BIOMEDICAL OPTICS, 2012, 17 (07)
[46] Endoscopic imaging of white matter fiber tracts using polarization-sensitive optical coherence tomography
DePaoli, Damon
Cote, Daniel C.
Bouma, Brett E.
Villiger, Martin
NEUROIMAGE, 2022, 264
[47] An algorithm for speckle noise reduction in endoscopic optical coherence tomography structural imaging
Potlov, A. Yu
Frolov, S., V
Proskurin, S. G.
SARATOV FALL MEETING 2018: OPTICAL AND NANO-TECHNOLOGIES FOR BIOLOGY AND MEDICINE, 2019, 11065
[48] Graphics Processing Unit-Based Ultrahigh Speed Real-Time Fourier Domain Optical Coherence Tomography
Zhang, Kang
Kang, Jin U.
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS, 2012, 18 (04) : 1270 - 1279
[49] Development of novel high-speed en face optical coherence tomography system using KTN optical beam deflector
Ohmi, Masato
Fukuda, Akihiro
Miyazu, Jun
Ueno, Masahiro
Toyoda, Seiji
Kobayashi, Junya
APPLIED PHYSICS EXPRESS, 2015, 8 (02) : 027001
[50] Optical Coherence Tomography Imaging of Normal, Chronologically Aged, Photoaged and Photodamaged Skin: A Systematic Review
Mamalis, Andrew
Ho, Derek
Jagdeo, Jared
DERMATOLOGIC SURGERY, 2015, 41 (09) : 993 - 1005

← 1 2 3 4 5 →