Cutaneous Melanoma Version 2.2019

被引：298

作者：

Coit, Daniel G. ^{[1
]}

Thompson, John A. ^{[2
]}

Albertini, Mark R. ^{[3
]}

Barker, Christopher ^{[1
]}

Carson, William E., III ^{[4
,5
]}

Contreras, Carlo ^{[6
]}

Daniels, Gregory A. ^{[7
]}

DiMaio, Dominick ^{[8
]}

Fields, Ryan C. ^{[9
,10
]}

Fleming, Martin D. ^{[11
]}

Freeman, Morganna ^{[12
]}

Galan, Anjela ^{[13
]}

Gastman, Brian ^{[14
,15
]}

Guild, Valerie ^{[16
]}

Johnson, Douglas ^{[17
]}

Joseph, Richard W. ^{[18
]}

Lange, Julie R. ^{[19
]}

Nath, Sameer ^{[20
]}

Olszanski, Anthony J. ^{[21
]}

Ott, Patrick ^{[22
]}

Gupta, Aparna Priyanath ^{[23
]}

Ross, Merrick, I ^{[24
]}

Salama, April K. ^{[25
]}

Skitzki, Joseph ^{[26
]}

Sosman, Jeffrey ^{[23
]}

Swetter, Susan M. ^{[27
]}

Tanabe, Kenneth K. ^{[28
]}

Wuthrick, Evan ^{[29
]}

McMillian, Nicole R. ^{[30
]}

Engh, Anita M. ^{[30
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA

[2] Fred Hutchinson Canc Res Ctr, Seattle Canc Care Alliance, 1124 Columbia St, Seattle, WA 98104 USA

[3] Univ Wisconsin, Carbone Canc Ctr, Madison, WI 53706 USA

[4] Ohio State Univ, Comprehens Canc Ctr, James Canc Hosp, Columbus, OH 43210 USA

[5] Ohio State Univ, Comprehens Canc Ctr, Solove Res Inst, Columbus, OH 43210 USA

[6] Univ Alabama Birmingham, Comprehens Canc Ctr, Birmingham, AL USA

[7] Univ Calif San Diego, Moores Canc Ctr, La Jolla, CA USA

[8] Fred & Pamela Buffett Canc Ctr, Omaha, NE USA

[9] Barnes Jewish Hosp, Siteman Canc Ctr, St Louis, MO 63110 USA

[10] Washington Univ, Sch Med, St Louis, MO 63130 USA

[11] Univ Tennessee, Hlth Sci Ctr, St Jude Childrens Res Hosp, Knoxville, TN 37996 USA

[12] City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USA

[13] Yale Canc Ctr, Smilow Canc Hosp, New Haven, CT USA

[14] Univ Hosp Seidman Canc Ctr, Case Comprehens Canc Ctr, Cleveland, OH USA

[15] Cleveland Clin Taussig Canc Inst, Cleveland, OH USA

[16] Aim Melanoma, Richmond, CA USA

[17] Vanderbilt Ingram Canc Ctr, Nashville, TN USA

[18] Mayo Clin, Canc Ctr, Rochester, MN USA

[19] Sidney Kimmel Comprehens Canc Ctr Johns Hopkins, Baltimore, MD USA

[20] Univ Colorado, Canc Ctr, Boulder, CO 80309 USA

[21] Fox Chase Canc Ctr, 7701 Burholme Ave, Philadelphia, PA 19111 USA

[22] Dana Farber Brigham & Womens Canc Ctr, Boston, MA USA

[23] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Evanston, IL 60208 USA

[24] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA

[25] Duke Canc Inst, Durham, NC USA

[26] Roswell Pk Comprehens Canc Ctr, Buffalo, NY USA

[27] Stanford Canc Inst, Stanford, CA USA

[28] Massachusetts Gen Hosp, Canc Ctr, Boston, MA 02114 USA

[29] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA

[30] Natl Comprehens Canc Network, Plymouth Meeting, PA USA

来源：

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2019年 / 17卷 / 04期

关键词：

COOPERATIVE-ONCOLOGY-GROUP; RANDOMIZED PHASE-III; HIGH-DOSE INTERFERON-ALPHA-2B; HIGH-RISK MELANOMA; DABRAFENIB PLUS TRAMETINIB; LONG-TERM SURVIVAL; RESECTED STAGE-III; ADVANCED BRAF(V600)-MUTANT MELANOMA; INVESTIGATOR-CHOICE CHEMOTHERAPY; MUTATED METASTATIC MELANOMA;

D O I：

10.6004/jnccn.2019.0018

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Cutaneous melanoma have been significantly revised over the past few years in response to emerging data on immune checkpoint inhibitor therapies and BRAF-targeted therapy. This article summarizes the data and rationale supporting extensive changes to the recommendations for systemic therapy as adjuvant treatment of resected disease and as treatment of unresectable or distant metastatic disease.

引用

页码：367 / 402

页数：36

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