Pediatric Herpes Simplex Virus Encephalitis Complicated by N-Methyl-D-aspartate Receptor Antibody Encephalitis

被引：24

作者：

Bamford, Alasdair ^{[1
,3
]}

Crowe, Belinda H. A. ^{[2
]}

Hacohen, Yael ^{[4
]}

Lin, Jean-Pierre ^{[5
]}

Clarke, Antonia ^{[6
]}

Tudor-Williams, Gareth ^{[1
,3
]}

Sancho-Shimizu, Vanessa ^{[3
]}

Vincent, Angela ^{[4
]}

Lim, Ming ^{[4
,5
]}

Pullaperuma, Sunil P. ^{[2
]}

机构：

[1] Imperial Coll Healthcare NHS Trust, St Marys Hosp, Dept Paediat Infect Dis, London, England

[2] Imperial Coll Healthcare NHS Trust, St Marys Hosp, Paediat Neurodisabil Serv, London, England

[3] Imperial Coll, Sect Paediat, London, England

[4] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Clin Neurosci, Oxford, England

[5] Evelina London Childrens Hosp, Guys & St Thomas NHS Fdn Trust, Childrens Neurosci, London, England

[6] St George Hosp, St Georges Hosp NHS Trust, Dept Paediat Neurol, London, England

来源：

JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY | 2015年 / 4卷 / 02期

关键词：

encephalitis; HSV; NMDAR; pediatric; plasmapheresis; CHILDREN;

D O I：

10.1093/jpids/piu054

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

N-methyl-D-aspartate receptor antibodies (NMDAR-Abs) can contribute to neurological relapse after herpes simplex virus encephalitis (HSE). We describe a child with NMDAR-Ab encephalitis after HSE, which was recognized and treated early. We discuss the case in the context of existing reports, and we propose a modified immunotherapy strategy to minimize risk of viral reactivation.

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收藏

页码：E17 / E21

页数：5

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