Primary Adrenal Insufficiency during Immune Checkpoint Inhibitor Treatment: Case Reports and Review of the Literature

被引：15

作者：

Salinas, Carlos ^{[1
]}

Renner, Alex ^{[1
]}

Rojas, Carlos ^{[1
,2
]}

Samtani, Suraj ^{[1
]}

Burotto, Mauricio ^{[1
,2
]}

机构：

[1] Med Oncol Serv Bradford Hill, Santiago, Chile

[2] Clin Univ Andes, Med Oncol Serv, Las Condes, Chile

来源：

CASE REPORTS IN ONCOLOGY | 2020年 / 13卷 / 02期

关键词：

Ipilimumab; Nivolumab; Primary adrenal insufficiency; Immune-related adverse events; NIVOLUMAB PLUS IPILIMUMAB; OPEN-LABEL; MULTICENTER;

D O I：

10.1159/000507652

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

As the indications and clinical use of immune checkpoint inhibitors increase, it is expected that we will face some of their less frequently reported complications. Primary adrenal insufficiency is one of them, and given its unspecific symptoms and potentially serious consequences, it is important to have a high degree of clinical suspicion. We present 3 cases and a review of the literature concerning its main clinical characteristics, diagnostics, and management.

引用

页码：621 / 626

页数：6

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