Thrombopoietin and Mean Platelet Volume in Patients With Ischemic Stroke

被引：21

作者：

Balcik, Ozlem Sahin ^{[2
]}

Bilen, Sule ^{[3
]}

Ulusoy, Ersin Kasim ^{[3
]}

Akdeniz, Derya ^{[1
]}

Uysal, Sema ^{[4
]}

Ikizek, Mustafa ^{[1
]}

Ak, Fikri ^{[3
]}

Kosar, Ali ^{[2
]}

机构：

[1] Fatih Univ, Dept Internal Med, Fac Med, TR-06510 Ankara, Turkey

[2] Fatih Univ, Dept Hematol, Fac Med, TR-06510 Ankara, Turkey

[3] Ankara Numune Training & Res Hosp, Dept Neurol, Ankara, Turkey

[4] Fatih Univ, Dept Biochem, Fac Med, TR-06510 Ankara, Turkey

来源：

CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS | 2013年 / 19卷 / 01期

关键词：

stroke; hypercoagulability; thrombosis; MYOCARDIAL-INFARCTION; CEREBRAL INFARCTION; PRIMARY REGULATOR; DISEASE; SIZE; THROMBOCYTOPENIA; SUBTYPE; COUNT;

D O I：

10.1177/1076029611434528

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective: The aim of this study was to evaluate mean platelet volume (MPV), thrombopoietin (TPO), and platelet levels in patients with ischemic stroke and compare this with healthy controls. Methods: We prospectively studied 50 patients with ischemic stroke and compared them with 37 control participants who have evaluated in internal medicine polyclinic and had no history of cerebrovascular events. All patients were within 24 hours after stroke; MPV and TPO were measured on admission. Results: Both TPO and MPV values were significantly higher in patients with stroke (P=.00; P=.001). Conclusion: Increased TPO levels may increase both platelet count and platelet size, resulting in more hemostatic tendency, which may contribute to the progression of ischemic stroke.

引用

页码：92 / 95

页数：4

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