Synthesis of substituted indenones and indanones by a Suzuki-Miyaura coupling/acid-promoted cyclisation sequence

被引：23

作者：

Butkevich, Alexey N. ^{[1
]}

Ranieri, Beatrice ^{[1
]}

Meerpoel, Lieven ^{[2
]}

Stansfield, Ian ^{[3
]}

Angibaud, Patrick ^{[3
]}

Corbu, Andrei ^{[1
]}

Cossy, Janine ^{[1
]}

机构：

[1] ESPCI ParisTech, Chim Organ Lab, CNRS, F-75231 Paris 05, France

[2] Janssen Res & Dev, B-2340 Beerse, Belgium

[3] Janssen Res & Dev, Oncol & Med Chem, F-27106 Val De Reuil, France

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2014年 / 12卷 / 05期

关键词：

FRIEDEL-CRAFTS REACTION; ONE-POT SYNTHESIS; C-H; CATALYZED ANNULATION; EFFICIENT SYNTHESIS; INTERNAL ALKYNES; ALLYLIC ALCOHOLS; VIROLA-SEBIFERA; 1-INDANONES; ACIDS;

D O I：

10.1039/c3ob41974f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot Suzuki-Miyaura cross-coupling/acid-catalyzed cyclisation leading to indenones and indanones in modest to good yields is reported.

引用

页码：728 / 731

页数：4

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