Efficient and enantioselective nitroaldol reaction catalyzed by copper Schiff-base complexes

被引：103

作者：

Gan, CS

Lai, GY

Zhang, ZH

Wang, ZY

Zhou, MM ^{[1
]}

机构：

[1] Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, Hefei 230026, Anhui, Peoples R China

[2] Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China

[3] NYU, Mt Sinai Sch Med, Dept Physiol & Biophys, Struct Biol Program, New York, NY 10029 USA

来源：

TETRAHEDRON-ASYMMETRY | 2006年 / 17卷 / 05期

基金：

美国国家卫生研究院; 中国国家自然科学基金;

关键词：

D O I：

10.1016/j.tetasy.2006.01.032

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Mild and efficient enantioselective nitroaldol reactions of nitromethane with various aldehydes were catalyzed by chiral copper Schiff-base complexes, which can be readily prepared from amino acid, yielding the corresponding adducts with high yields and good enantiometric excess (ee). (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：725 / 728

页数：4

共 36 条

[1] Self-assembly of heterobimetallic complexes and reactive nucleophiles: A general strategy for the activation of asymmetric reactions promoted by heterobimetallic catalysts [J].