Physical fitness and physical activity association with cognitive function and quality of life: baseline cross-sectional analysis of the PREDIMED-Plus trial

被引：57

作者：

Daimiel, Lidia ^{[1
]}

Martinez-Gonzalez, Miguel A. ^{[2
,3
,4
]}

Corella, Dolores ^{[2
,5
]}

Salas-Salvado, Jordi ^{[2
,6
]}

Schroder, Helmut ^{[7
,8
]}

Vioque, Jesus ^{[7
,9
]}

Romaguera, Dora ^{[2
,10
]}

Alfredo Martinez, J. ^{[2
,11
,12
]}

Warnberg, Julia ^{[2
,13
]}

Lopez-Miranda, Jose ^{[2
,14
]}

Estruch, Ramon ^{[2
,15
]}

Cano-Ibanez, Naomi ^{[7
,16
]}

Alonso-Gomez, Angel ^{[2
,17
,18
]}

Tur, Josep A. ^{[2
,10
,19
]}

Tinahones, Francisco J. ^{[2
,20
]}

Serra-Majem, Lluis ^{[2
,21
]}

Mico-Perez, Rafael M. ^{[22
]}

Lapetra, Jose ^{[2
,23
]}

Galdon, Alba ^{[24
]}

Pinto, Xavier ^{[2
,25
]}

Vidal, Josep ^{[26
,27
]}

Mico, Victor ^{[1
]}

Colmenarejo, Gonzalo ^{[28
]}

Gaforio, Jose J. ^{[7
,29
]}

Matia, Pilar ^{[30
]}

Ros, Emilio ^{[2
,27
]}

Buil-Cosiales, Pilar ^{[2
,31
]}

Vazquez-Ruiz, Zenaida ^{[2
,3
]}

Sorli, Jose, V ^{[2
,5
]}

Paz Graniel, Indira ^{[2
,6
]}

Cuenca-Royo, Aida ^{[32
]}

Gisbert-Selles, Cristina ^{[8
,33
]}

Galmes-Panades, Aina M. ^{[2
,10
]}

Angeles Zulet, M. ^{[2
,11
,12
]}

Garcia-Rios, Antonio ^{[2
,14
]}

Diaz-Lopez, Andres ^{[2
,6
]}

de la Torre, Rafael ^{[7
,8
]}

Galilea-Zabalza, Inigo ^{[31
]}

Ordovas, Jose M. ^{[1
,34
,35
]}

机构：

[1] CEI UAM CSIC, IMDEA Food, Nutr Genom & Epigen Grp, Madrid, Spain

[2] Inst Salud Carlos III ISCIII, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid, Spain

[3] Univ Navarra, Dept Prevent Med & Publ Hlth, IDISNA, Pamplona, Spain

[4] Harvard TH Chan Sch Publ Hlth, Dept Nutr, Boston, MA USA

[5] Univ Valencia, Dept Prevent Med, Valencia, Spain

[6] Univ Rovira & Virgili, Dept Bioquim & Biotecnol, Unitat Nutr Hosp Univ San Joan Reus, Inst Invest PereVirgili IISPV, Reus, Spain

[7] Inst Salud Carlos III ISCIII, CIBER Epidemiol & Salud Pobl CIBERESP, Madrid, Spain

[8] Inst Hosp del Mar Invest Med Municipal Invest Med, Unit Cardiovasc Risk & Nutr, Barcelona, Spain

[9] Inst Invest Sanitaria & Biomed Alicante, ISABIAL, Alicante, Spain

[10] Hlth Res Inst Balearic Isl IdISBa, Palma De Mallorca, Spain

[11] Univ Navarra, Dept Nutr Food Sci & Physiol, Pamplona, Spain

[12] CEI UAM CSIC, IMDEA Food, Cardiometab Nutr Grp, Madrid, Spain

[13] Univ Malaga, Inst Invest Biomed Malaga IBIMA, Sch Hlth Sci, Dept Nursing, Malaga, Spain

[14] Univ Cordoba, Reina Sofia Univ Hosp, Maimonides Biomed Res Inst Cordoba IMIBIC, Lipids & Atherosclerosis Unit,Dept Internal Med, Cordoba, Spain

[15] Univ Barcelona, Hosp Clin, Dept Internal Med, IDIBAPS, Barcelona, Spain

[16] Univ Granada, Dept Prevent Med, Granada, Spain

[17] Univ Basque Country, UPV EHU, Bioaraba Hlth Res Inst, Vitoria, Spain

[18] Univ Basque Country, UPV EHU, Osakidetza Basque Hlth Serv, Araba Univ Hosp, Vitoria, Spain

[19] Univ Balearic Isl, Res Grp Community Nutr & Oxidat Stress, Palma De Mallorca, Spain

[20] Univ Malaga, Virgen de la Victoria Hosp, Inst Invest Biomed Malaga IBIMA, Dept Endocrinol, Malaga, Spain

[21] Univ Las Palmas Gran Canaria, Res Inst Biomed & Hlth Sci IUIBS, Ctr Hosp Univ Insular Materno Infantil CHUIMI, Prevent Med Serv,Canarian Hlth Serv, Las Palmas Gran Canaria, Spain

[22] Catedra Cronicidad Univ Miguel Hernandez, Semergen, Spain

[23] Dist Sanitario Atenc Primaria Sevilla, Res Unit, Dept Family Med, Seville, Spain

[24] Fdn Jimenez Diaz, Dept Endocrinol, Madrid, Spain

[25] Hosp Univ Bellvitge, Lipids & Vasc Risk Unit, Internal Med, Barcelona, Spain

[26] Inst Salud Carlos III ISCIII, CIBER Diabet & Enfermedades Metab CIBERDEM, Madrid, Spain

[27] Univ Barcelona, Hosp Clin, Dept Endocrinol, IDIBAPS, Barcelona, Spain

[28] CEI UAM CSIC, Biostat & Bioinformat Unit, IMDEA Food, Madrid, Spain

[29] Univ Jaen, Ctr Adv Studies Olive Grove & Olive Oils, Jaen, Spain

[30] Inst Invest Sanitaria Hosp Clin San Carlos IdISSC, Dept Endocrinol & Nutr, Madrid, Spain

[31] Serv Navarro Salud, Primary Hlth Care, Pamplona, Spain

[32] Inst Hosp del Mar Invest Med Municipal Invest Med, Integrat Pharmacol & Syst Neurosci, Barcelona, Spain

[33] Ctr San Vicente Raspeig, Primary Hlth Care, Alicante, Spain

[34] Tufts Univ, JM USDA Human Nutr Res Ctr Aging, Nutr & Genom Lab, Boston, MA 02111 USA

[35] Ctr Nacl Invest Cardiovasc CNIC, Dept Cardiovasc Epidemiol & Populat Genet, Madrid, Spain

来源：

SCIENTIFIC REPORTS | 2020年 / 10卷 / 01期

基金：

欧洲研究理事会;

关键词：

OLDER-ADULTS; MEDITERRANEAN DIET; AEROBIC EXERCISE; PERFORMANCE; DEMENTIA; STRENGTH; MEMORY;

D O I：

10.1038/s41598-020-59458-6

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Physical activity (PA) has been hypothesized to be effective to maintaining cognitive function and delay cognitive decline in the elderly, but physical fitness (PF) could be a better predictor of cognitive function. We aimed to study the association between PA and PF with cognitive function and quality of life using cross-sectional data from 6874 participants of the PREDIMED-Plus trial (64.9 +/- 4.9 years, 48.5% female). PF and PA were measured with a Chair Stand Test, the REGICOR and Rapid Assessment Physical Activity questionnaires. Cognitive function was measured with Mini-mental State Examination, Control Oral Word Association Test, Trail Making Test and Digit Span tests; whereas health-related quality of life was assessed with the SF36-HRQL test. Cognitive and quality of life scores were compared among PF quartiles and PA levels (low, moderate and high) with ANCOVA and with Chair Stand repetitions and energy expenditure from total PA with multivariable linear regression adjusted for confounding factors. PF associated with higher scores in phonemic and semantic verbal fluency tests and with lower TMT A time. However, PA was not associated with the neurocognitive parameters evaluated. Both PF and PA levels were strongly associated with a better quality of life. We concluded that PF, but not PA, is associated with a better cognitive function.

引用

页数：12

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