Semisynthetic DNA-protein conjugates for fabrication of nucleic acid based nanostructures

被引：0
作者：
Rabe, Kersten S. [1 ]
Feldkamp, Udo [1 ]
Niemeyer, Christof M. [1 ]
机构：
[1] Tech Univ Dortmund, Fak Chem, D-44227 Dortmund, Germany
来源：
DNA-BASED NANODEVICES | 2008年 / 1062卷
关键词：
Self-assembly; DNA-protein conjugates; redoxproteins; P450; DNA-sequence design;
D O I：
暂无
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
We here report on die developments of semisynthetic DNA-protein conjugates and their assembly into multi-component nanostructures. We describe the improvement of the DNA sequences embedded in such nanostructures by computational and analytical methods. Moreover, we report on the exploration of novel DNA conjugates of streptavidin or redox proteins with improved properties for the assembly of nucleic acid based nanostructures.
引用
收藏
页码：19 / 32
页数：14
相关论文
共 48 条
[1]   Direct readout of protein-protein interactions by mass spectrometry from protein-DNA microarrays [J].
Becker, CFW ;
Wacker, R ;
Bouschen, W ;
Seidel, R ;
Kolaric, B ;
Lang, P ;
Schroeder, H ;
Müller, O ;
Niemeyer, CM ;
Spengler, B ;
Goody, RS ;
Engelhard, M .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (46) :7635-7639
[2]  
BECKER CFW, 2007, AM PEPTIDE S, V9, P725
[3]  
Berg J.M., 2015, Oxidative Phosphorylation, Veight
[4]   MOLECULAR ENGINEERING - AN APPROACH TO THE DEVELOPMENT OF GENERAL CAPABILITIES FOR MOLECULAR MANIPULATION [J].
DREXLER, KE .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-PHYSICAL SCIENCES, 1981, 78 (09) :5275-5278
[5]   Rational design of DNA nanoarchitectures [J].
Feldkamp, U ;
Niemeyer, CM .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (12) :1856-1876
[6]   Software tools for DNA sequence design [J].
Feldkamp, Udo ;
Rauhe, Hilmar ;
Banzhaf, Wolfgang .
Genetic Programming and Evolvable Machines, 2003, 4 (02) :153-171
[7]   Microarray-based in vitro evaluation of DNA oligomer libraries designed in silico [J].
Feldkamp, U ;
Wacker, R ;
Schroeder, H ;
Banzhaf, W ;
Niemeyer, CM .
CHEMPHYSCHEM, 2004, 5 (03) :367-372
[8]   Rational engineering of dynamic DNA systems [J].
Feldkamp, Udo ;
Niemeyer, Christof M. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2008, 47 (21) :3871-3873
[9]   Design and evaluation of single-stranded DNA carrier molecules for DNA-directed assembly [J].
Feldkamp, Udo ;
Schroeder, Hendrik ;
Niemeyer, Christof M. .
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2006, 23 (06) :657-666
[10]   Covalent hemin-DNA adducts for generating a novel class of artificial heme enzymes [J].
Fruk, L ;
Niemeyer, CM .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (17) :2603-2606
12345