Mammalian target of rapamycin (mTOR): Pro- and anti-apoptotic

[1] A role of the kinase mTOR in cellular transformation induced by the oncoproteins P3k and Akt [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (01) : 136 - 141

[2] Oncogenic kinase signalling [J]. NATURE, 2001, 411 (6835) : 355 - 365

[3] Activation of p70 ribosomal protein S6 kinase is an essential step in the DNA damage-dependent signaling pathway responsible for the ultraviolet B-mediated increase in interstitial collagenase (MMP-1) and stromelysin-1 (MMP-3) protein levels in human dermal fibroblasts [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (06) : 4336 - 4344

[4] Damaged microtubules can inactivate BCL-2 by means of the mTOR kinase [J]. ONCOGENE, 2001, 20 (43) : 6172 - 6180

[5] Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target. of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2001, 194 (08) : 1097 - 1110

[6] Signalling pathways regulating the dephosphorylation of Ser729 in the hydrophobic domain of protein kinase Cε upon cell passage [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (13) : 10437 - 10442

[7] Apoptosis and karyogamy in syncytia induced by the HIV-1-envelope glycoprotein complex [J]. CELL DEATH AND DIFFERENTIATION, 2000, 7 (11) : 1137 - 1139

[8] Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex:: Role of mitochondria and caspases [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2000, 192 (08) : 1081 - 1092

[9] p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (17) : 9666 - 9670

[10] Huang SL, 2001, CANCER RES, V61, P3373

[1] A role of the kinase mTOR in cellular transformation induced by the oncoproteins P3k and Akt [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (01) : 136 - 141

[2] Oncogenic kinase signalling [J]. NATURE, 2001, 411 (6835) : 355 - 365

[3] Activation of p70 ribosomal protein S6 kinase is an essential step in the DNA damage-dependent signaling pathway responsible for the ultraviolet B-mediated increase in interstitial collagenase (MMP-1) and stromelysin-1 (MMP-3) protein levels in human dermal fibroblasts [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (06) : 4336 - 4344

[4] Damaged microtubules can inactivate BCL-2 by means of the mTOR kinase [J]. ONCOGENE, 2001, 20 (43) : 6172 - 6180

[5] Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target. of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2001, 194 (08) : 1097 - 1110

[6] Signalling pathways regulating the dephosphorylation of Ser729 in the hydrophobic domain of protein kinase Cε upon cell passage [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (13) : 10437 - 10442

[7] Apoptosis and karyogamy in syncytia induced by the HIV-1-envelope glycoprotein complex [J]. CELL DEATH AND DIFFERENTIATION, 2000, 7 (11) : 1137 - 1139

[8] Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex:: Role of mitochondria and caspases [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2000, 192 (08) : 1081 - 1092

[9] p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (17) : 9666 - 9670

[10] Huang SL, 2001, CANCER RES, V61, P3373