The 6-Minute Walk Test as a Tool for Determining Exercise Capacity and Prognosis in Patients with Silicosis

被引：15

作者：

Blanco Perez, Jose Jesus ^{[1
,2
]}

Arnalich Montiel, Victoria ^{[1
]}

Salgado-Barreira, Angel ^{[3
]}

Alvarez Moure, Maria Angel ^{[4
]}

Caldera Diaz, Adriana Carolina ^{[4
]}

Cerdeira Dominguez, Luz ^{[5
]}

Gonzalez Bello, M. Elena ^{[5
]}

Fernandez Villar, Alberto ^{[1
]}

Gonzalez Barcala, Francisco Javier ^{[6
]}

机构：

[1] Complexo Hosp Univ Vigo, Serv Neumoloxia, Hosp Alvaro Cunqueiro, Vigo, Pontevedra, Spain

[2] Inst Invest Sanitaria Galicia Sur, Invest Rheumatol & Immunomediated Dis IRIDIS Grp, Vigo, Pontevedra, Spain

[3] Inst Invest Sanitaria Galicia Sur, Unidad Metodol & Estadist, Vigo, Pontevedra, Spain

[4] Complexo Hosp Univ Vigo, Serv Radiol, Hosp Alvaro Cunqueiro, Vigo, Pontevedra, Spain

[5] Complexo Hosp Univ Vigo, Unidad Pruebas Func Resp, Personal Enfermeria, Hosp Alvaro Cunqueiro Vigo, Vigo, Pontevedra, Spain

[6] Complexo Hosp Univ Santiago de Compostela, Serv Neumoloxia, Spanish Biomed Res Networking Ctr CIBERES, La Coruna, Spain

来源：

ARCHIVOS DE BRONCONEUMOLOGIA | 2019年 / 55卷 / 02期

关键词：

Silicosis; Six-minute walk test; Lung function tests; COMPUTED-TOMOGRAPHY; DISTANCE; COPD; STANDARDIZATION; DYSPNEA;

D O I：

10.1016/j.arbres.2018.07.004

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Objective: To evaluate exercise capacity using the 6-minute walk test (6MWT) in patients with complicated silicosis, and to determine how results shape the prognostic value of 6MWT for hospitalization and mortality. Method: Prospective observational study in 143 patients with complicated silicosis who performed the 6MWT in our outpatient pulmonology clinic between 2009 and the end of 2016. Lung function tests, computed tomography findings and 6MWT parameters (distance walked and oxygen desaturation) were evaluated. Results: Patients with complicated silicosis walked 387 +/- 92 m. Results deteriorated as silicosis severity increased; category A: 407 +/- 97 m, B: 370 +/- 88 m, and C: 357 +/- 68 m (P=.022). The 6MWT correlated positively with lung function and inversely with dyspnea determined by mMRC (P<.001). Patients with moderate/severe emphysema and greater C 190 presented a worse result on 6MWT. Patients who walked < 350 m had more hospitalizations (3.7 +/- 4.0) than those who walked > 350 m (1.1 +/- 2.9). There was an impact on survival: non-survivors walked 327.9 +/- 73.0 m, while survivors walked 404.5 +/- 89.7 m (P<.001). Conclusions: Spirometry values and category of complicated silicosis correlated with 6MWT and distance walked was a prognostic factor for hospitalization and mortality. The 6MWT is a useful tool in occupational health for monitoring patients with silicosis. (C) 2018 SEPAR. Published by Elsevier Espana, S.L.U. All rights reserved.

引用

页码：88 / 92

页数：5

共 33 条

[1] Prognostic value of variables derived from the six-minute walk test in patients with COPD: Results from the ECLIPSE study [J].

Andrianopoulos, Vasileios ;

Wouters, Emiel F. M. ;

Pinto-Plata, Victor M. ;

Vanfleteren, Lowie E. G. W. ;

Bakke, Per S. ;

Franssen, Frits M. E. ;

Agusti, Alvar ;

MacNee, William ;

Rennard, Stephen I. ;

Tal-Singer, Ruth ;

Vogiatzis, Ioannis ;

Vestbo, Jorgen ;

Celli, Bartolome R. ;

Spruit, Martijn A. .

RESPIRATORY MEDICINE, 2015, 109 (09) :1138-1146

[2] The Value and Application of the 6-Minute-Walk Test in Idiopathic Pulmonary Fibrosis [J].

Brown, A. Whitney ;

Nathan, Steven D. .

ANNALS OF THE AMERICAN THORACIC SOCIETY, 2018, 15 (01) :3-10

[3] Survival after pulmonary rehabilitation in patients with COPD: impact of functional exercise capacity and its changes [J].

Camillo, Carlos A. ;

Langer, Daniel ;

Osadnik, Christian R. ;

Pancini, Lisa ;

Demeyer, Heleen ;

Burtin, Chris ;

Gosselink, Rik ;

Decramer, Marc ;

Janssens, Wim ;

Troosters, Thierry .

INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 2016, 11 :2671-2679

[4] COPD phenotypes in biomass smoke-versus tobacco smoke-exposed Mexican women [J].

Camp, Pat G. ;

Ramirez-Venegas, Alejandra ;

Sansores, Raul H. ;

Alva, Luis F. ;

McDougall, Jill E. ;

Sin, Don D. ;

Pare, Peter D. ;

Mueller, Nestor L. ;

Silva, C. Isabela S. ;

Rojas, Carlos E. ;

Coxson, Harvey O. .

EUROPEAN RESPIRATORY JOURNAL, 2014, 43 (03) :725-734

[5] The 6-min walk distance in healthy subjects: reference standards from seven countries [J].

Casanova, C. ;

Celli, B. R. ;

Barria, P. ;

Casas, A. ;

Cote, C. ;

de Torres, J. P. ;

Jardim, J. ;

Lopez, M. V. ;

Marin, J. M. ;

Montes de Oca, M. ;

Pinto-Plata, V. ;

Aguirre-Jaime, A. .

EUROPEAN RESPIRATORY JOURNAL, 2011, 37 (01) :150-156

[6] Distance and Oxygen Desaturation During the 6-min Walk Test as Predictors of Long-term Mortality in Patients With COPD [J].

Casanova, Ciro ;

Cote, Claudia ;

Marin, Jose M. ;

Pinto-Plata, Victor ;

de Torres, Juan P. ;

Aguirre-Jaime, Armando ;

Vassaux, Carlos ;

Celli, Bartolome R. .

CHEST, 2008, 134 (04) :746-752

[7] A NEW METHOD OF CLASSIFYING PROGNOSTIC CO-MORBIDITY IN LONGITUDINAL-STUDIES - DEVELOPMENT AND VALIDATION [J].

CHARLSON, ME ;

POMPEI, P ;

ALES, KL ;

MACKENZIE, CR .

JOURNAL OF CHRONIC DISEASES, 1987, 40 (05) :373-383

[8] Role of computed tomography in quantitative assessment of emphysema [J].

Choromanska, Agnieszka ;

Macura, Katarzyna J. .

POLISH JOURNAL OF RADIOLOGY, 2012, 77 (01) :28-36

[9]

Cozza I, 2013, EUR RESP J S57, V42

[10] ATS statement: Guidelines for the six-minute walk test [J].

Crapo, RO ;

Casaburi, R ;

Coates, AL ;

Enright, PL ;

MacIntyre, NR ;

McKay, RT ;

Johnson, D ;

Wanger, JS ;

Zeballos, RJ ;

Bittner, V ;

Mottram, C .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2002, 166 (01) :111-117

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